We present machine learning models trained on experimental data to predict room-
temperature solubility for any polymer–solvent pair. The new models are a significant …

Fisetin (FIS), a senolytic flavonoid, mitigates age-related neuroprotective changes. An
amorphous FIS dispersion with a co-carrier was prepared using supercritical fluid extraction …

Improving drug solubility is necessary for formulations of poorly water-soluble drugs,
especially for oral administration. Amorphous solid dispersions (ASDs) are widely used in …

Ocular fungal infections can pose severe health conditions that may develop into vision
impairment and blindness. Sertaconazole (STZ) is a widely used antifungal; however, its low …

Four model polymers, representing (i) amorphous homopolymers (Kollidon K30, K30),(ii)
amorphous heteropolymers (Kollidon VA64, KVA),(iii) semi-crystalline homopolymers …

BCS class II drugs exhibit low aqueous solubility and high permeability. Such drugs often
have an incomplete or erratic absorption profile. This study aimed to predict the effects of β …

Rosuvastatin (RSV) is a widely used cholesterol-lowering medication, but its limited
bioavailability due to its susceptibility to stomach pH and extensive first-pass metabolism …

Loratadine (LRD), a non-sedating and slow-acting antihistamine, is often given in
combination with short-onset chlorpheniramine maleate (CPM) to increase efficacy …

An ionic liquid based on the monomeric choline, specifically [2-(methacryloyloxy) ethyl]-
trimethylammonium chloride (TMAMA), underwent biofunctionalization through an ion …

Objective To improve the biological and toxicological properties of Mefenamic acid (MA), the
galactosylated prodrug of MA named MefeGAL was included in polymeric solid dispersions …