Non-excitatory amino acids, melatonin, and free radicals: examining the role in stroke and aging

VJ Carretero, E Ramos, P Segura-Chama… - Antioxidants, 2023 - mdpi.com
The aim of this review is to explore the relationship between melatonin, free radicals, and
non-excitatory amino acids, and their role in stroke and aging. Melatonin has garnered …

Vincamine, from an antioxidant and a cerebral vasodilator to its anticancer potential

Y Ren, K DeRose, L Li, JC Gallucci, J Yu… - Bioorganic & Medicinal …, 2023 - Elsevier
Vincamine is a naturally occurring indole alkaloid showing antioxidant activity and has been
used clinically for the prevention and treatment of cerebrovascular disorders and …

Novel Multi-antioxidant Approach for ischemic stroke therapy targeting the role of oxidative stress

C Briones-Valdivieso, F Briones, S Orellana-Urzúa… - Biomedicines, 2024 - mdpi.com
Stroke is a major contributor to global mortality and disability. While reperfusion is essential
for preventing neuronal death in the penumbra, it also triggers cerebral ischemia …

Intranasal Drug Delivery by Nanotechnology: Advances in and Challenges for Alzheimer's Disease Management

S Dighe, S Jog, M Momin, S Sawarkar, A Omri - Pharmaceutics, 2023 - mdpi.com
Alzheimer's disease, a progressive neurodegenerative condition, is characterized by a
gradual decline in cognitive functions. Current treatment approaches primarily involve the …

ADVANCES IN ALZHEIMER'S DISEASE: A MULTIFACETED REVIEW OF POTENTIAL THERAPIES AND DIAGNOSTIC TECHNIQUES FOR EARLY DETECTION

M Sharma, P Pal, SK Gupta - Neurochemistry International, 2024 - Elsevier
Alzheimer's disease (AD) remains one of the most formidable neurological disorders,
affecting millions globally. This review provides a holistic overview of the therapeutic …

Preparation, characterization, antioxidant activities, and determination of anti-Alzheimer effects of PLGA-based DDSs containing ferulic acid

KN Arınmış, HT Kıyan, AA Ozturk - ACS omega, 2024 - ACS Publications
Nanoparticle (NP) systems have attracted the attention of researchers in recent years due to
their advantages, such as modified release features, increased therapeutic efficacy, and …

Protective effect of flavonoids on oxidative stress injury in Alzheimer's disease

K Wang, X Chen - Natural Product Research, 2024 - Taylor & Francis
Alzheimer's disease (AD) is the most common neurodegenerative disease, which is mainly
caused by the damage of the structure and function of the central nervous system. At …

Phenolic Compounds of Phlomis tuberosa by LC–MS/MS‐Determination of Antioxidant Activity, Molecular Docking, and Enzyme Inhibition Profiles

L Guven, A Erturk, M Koca, I Gulcin - ChemistrySelect, 2023 - Wiley Online Library
Phlomis species have traditionally been employed for the treatment of a number of ailments
such as influenza, the common cold, asthma, bronchitis, coughs, hemorrhoids, ulcers, and …

[HTML][HTML] Plant-derived nanovesicles: Promising therapeutics and drug delivery nanoplatforms for brain disorders

R Wang, Y Zhang, Y Guo, W Zeng, J Li, J Wu, N Li… - Fundamental …, 2023 - Elsevier
Abstract Plant-derived nanovesicles (PDNVs), including plant extracellular vesicles (EVs)
and plant exosome-like nanovesicles (ELNs), are natural nano-sized membranous vesicles …

Higher oxidative balance score decreases risk of stroke in US adults: evidence from a cross-sectional study

F Zhan, G Lin, K Duan, B Huang, L Chen… - Frontiers in …, 2023 - frontiersin.org
Background The oxidative balance score (OBS) can be used to represent the overall burden
of oxidative stress in an individual. This study aimed to explore the association between the …