Functional materials for subcellular targeting strategies in cancer therapy: progress and prospects
Y Cheng, Z Qu, Q Jiang, T Xu, H Zheng, P Ye… - Advanced …, 2023 - Wiley Online Library
Neoadjuvant and adjuvant therapies have made significant progress in cancer treatment.
However, tumor adjuvant therapy still faces challenges due to the intrinsic heterogeneity of …
However, tumor adjuvant therapy still faces challenges due to the intrinsic heterogeneity of …
The role of extracellular vesicles in the treatment of prostate cancer
C Hu, Q Chen, T Wu, X Du, Y Dong, Z Peng, W Xue… - Small, 2024 - Wiley Online Library
Prostate cancer (PCa) has become a public health concern in elderly men due to an ever‐
increasing number of estimated cases. Unfortunately, the available treatments are …
increasing number of estimated cases. Unfortunately, the available treatments are …
Endoplasmic reticulum-targeted aggregation-induced emission luminogen for synergetic tumor ablation with glibenclamide
Y Wu, X Chen, L Zhu, D Wang, X Li… - … Applied Materials & …, 2023 - ACS Publications
Photodynamic therapy based on fluorescence illumination of subcellular organelles and in
situ bursts of reactive oxygen species (ROS) has been recognized as a promising strategy …
situ bursts of reactive oxygen species (ROS) has been recognized as a promising strategy …
Acetylshikonin induces apoptosis through the endoplasmic reticulum stress‐activated PERK/eIF2α/CHOP axis in oesophageal squamous cell carcinoma
YJ Yuan, S Liu, H Yang, JL Xu, J Zhai… - Journal of Cellular …, 2024 - Wiley Online Library
Acetylshikonin (AS) is an active component of Lithospermum erythrorhizon Sieb. et Zucc that
exhibits activity against various cancers; however, the underlying mechanisms of AS against …
exhibits activity against various cancers; however, the underlying mechanisms of AS against …
Copper Increases the Sensitivity of Cholangiocarcinoma Cells to Tripterine by Inhibiting TMX2‐Mediated Unfolded Protein Reaction Activation
H Liu, L Xu, Y Zhang, Y Xie, L Wang… - Advanced …, 2023 - Wiley Online Library
Chemotherapy‐induced adaptive resistance is a significant factor that contributes to low
therapeutic efficacy in tumor cells. The unfolded protein response (UPR) is a key mechanism …
therapeutic efficacy in tumor cells. The unfolded protein response (UPR) is a key mechanism …
Label-Free Single-Cell SERS Detection and Fluorescence Imaging of Molecular Responses to Endoplasmic Reticulum Stress under Electrical Stimulation
C Zhang, G Qi, J Kong, X Diao, X Ju, J Wang… - Analytical …, 2023 - ACS Publications
The endoplasmic reticulum (ER) is one of the most important organelles in eukaryotic cells,
in which most proteins and lipids are synthesized to regulate complex cellular processes …
in which most proteins and lipids are synthesized to regulate complex cellular processes …
[HTML][HTML] Prostate cancer research: tools, cell types, and molecular targets
AY Liu - Frontiers in Oncology, 2024 - frontiersin.org
Multiple cancer cell types are found in prostate tumors. They are either luminal-like
adenocarcinoma or less luminal-like and more stem-like non-adenocarcinoma and small …
adenocarcinoma or less luminal-like and more stem-like non-adenocarcinoma and small …
Natural compound Alternol actives multiple endoplasmic reticulum stress-responding pathways contributing to cell death
W Liu, C He, C Li, S Ye, J Zhao, C Zhu… - Frontiers in …, 2024 - frontiersin.org
Background: Alternol is a small molecular compound isolated from the fermentation of a
mutant fungus obtained from Taxus brevifolia bark. Our previous studies showed that …
mutant fungus obtained from Taxus brevifolia bark. Our previous studies showed that …
Ultrastructural analysis of prostate cancer tissue provides insights into androgen-dependent adaptations to membrane contact site establishment
LM Butler, E Evergren - Frontiers in Oncology, 2023 - frontiersin.org
Membrane trafficking and organelle contact sites are important for regulating cell
metabolism and survival; processes often deregulated in cancer. Prostate cancer is the …
metabolism and survival; processes often deregulated in cancer. Prostate cancer is the …
CCT020312 exerts anti-prostate cancer effect by inducing G1 cell cycle arrest, apoptosis and autophagy through activation of PERK/eIF2α/ATF4/CHOP signaling
D Zhou, M Yin, B Kang, X Yu, H Zeng, B Chen… - Biochemical …, 2024 - Elsevier
Abstract PERK/eIF2α/ATF4/CHOP signaling pathway is one of three major branches of
unfolded protein response (UPR) and has been implicated in tumor progression …
unfolded protein response (UPR) and has been implicated in tumor progression …