Neoadjuvant and adjuvant therapies have made significant progress in cancer treatment.
However, tumor adjuvant therapy still faces challenges due to the intrinsic heterogeneity of …

Prostate cancer (PCa) has become a public health concern in elderly men due to an ever‐
increasing number of estimated cases. Unfortunately, the available treatments are …

Photodynamic therapy based on fluorescence illumination of subcellular organelles and in
situ bursts of reactive oxygen species (ROS) has been recognized as a promising strategy …

Acetylshikonin (AS) is an active component of Lithospermum erythrorhizon Sieb. et Zucc that
exhibits activity against various cancers; however, the underlying mechanisms of AS against …

Chemotherapy‐induced adaptive resistance is a significant factor that contributes to low
therapeutic efficacy in tumor cells. The unfolded protein response (UPR) is a key mechanism …

The endoplasmic reticulum (ER) is one of the most important organelles in eukaryotic cells,
in which most proteins and lipids are synthesized to regulate complex cellular processes …

Multiple cancer cell types are found in prostate tumors. They are either luminal-like
adenocarcinoma or less luminal-like and more stem-like non-adenocarcinoma and small …

Background: Alternol is a small molecular compound isolated from the fermentation of a
mutant fungus obtained from Taxus brevifolia bark. Our previous studies showed that …

Membrane trafficking and organelle contact sites are important for regulating cell
metabolism and survival; processes often deregulated in cancer. Prostate cancer is the …

Abstract PERK/eIF2α/ATF4/CHOP signaling pathway is one of three major branches of
unfolded protein response (UPR) and has been implicated in tumor progression …