The importance of antimicrobial resistance in medical mycology
Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …
[HTML][HTML] The influence of evolutionary history on human health and disease
Nearly all genetic variants that influence disease risk have human-specific origins; however,
the systems they influence have ancient roots that often trace back to evolutionary events …
the systems they influence have ancient roots that often trace back to evolutionary events …
The fungal cell wall: structure, biosynthesis, and function
The molecular composition of the cell wall is critical for the biology and ecology of each
fungal species. Fungal walls are composed of matrix components that are embedded and …
fungal species. Fungal walls are composed of matrix components that are embedded and …
PHI-base: the pathogen–host interactions database
The pathogen–host interactions database (PHI-base) is available at www. phi-base. org. PHI-
base contains expertly curated molecular and biological information on genes proven to …
base contains expertly curated molecular and biological information on genes proven to …
Drug repurposing for antimicrobial discovery
Antimicrobial resistance continues to be a public threat on a global scale. The ongoing need
to develop new antimicrobial drugs that are effective against multi-drug-resistant pathogens …
to develop new antimicrobial drugs that are effective against multi-drug-resistant pathogens …
A marine microbiome antifungal targets urgent-threat drug-resistant fungi
New antifungal drugs are urgently needed to address the emergence and transcontinental
spread of fungal infectious diseases, such as pandrug-resistant Candida auris. Leveraging …
spread of fungal infectious diseases, such as pandrug-resistant Candida auris. Leveraging …
Trypanosoma cruzi genetic diversity: Something new for something known about Chagas disease manifestations, serodiagnosis and drug sensitivity
B Zingales - Acta tropica, 2018 - Elsevier
The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete typing units (DTUs) …
widely recognized. At present, T. cruzi is partitioned into seven discrete typing units (DTUs) …
Molecular evolution of antifungal drug resistance
The fungal pathogens Candida albicans, Cryptococcus neoformans, and Aspergillus
fumigatus have transitioned from a rare curiosity to a leading cause of human mortality. The …
fumigatus have transitioned from a rare curiosity to a leading cause of human mortality. The …
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need
The WHO recognizes human African trypanosomiasis, Chagas disease and the
leishmaniases as neglected tropical diseases. These diseases are caused by parasitic …
leishmaniases as neglected tropical diseases. These diseases are caused by parasitic …
Pnictogens in medicinal chemistry: evolution from erstwhile drugs to emerging layered photonic nanomedicine
Pnictogens (the non-metal phosphorus, metalloids arsenic and antimony, and metal
bismuth) possess diverse chemical characteristics that support the formation of extended …
bismuth) possess diverse chemical characteristics that support the formation of extended …