The pathoetiology and pathophysiology of motor neuron loss in amyotrophic lateral sclerosis
(ALS) are still to be determined, with only a small percentage of ALS patients having a …

Viral infections constitute a tectonic convulsion in the normophysiology of the hosts. The
current coronavirus disease 2019 (COVID-19) pandemic is not an exception, and therefore …

Influenza virus infection is one of the strongest pathogenic factors for the development of
acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). However, the underlying …

Introduction: Tryptophan is the precursor of kynurenine pathway (KP) metabolites which
regulate immune tolerance, energy metabolism, and vascular tone. Since these processes …

Abstract Objectives Primary Sjögren's syndrome (pSS) is a complex systemic autoimmune
disease whose clinical spectrum extends from sicca syndrome to systemic involvement. T …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a member of the
coronavirus family that causes the novel coronavirus disease first diagnosed in 2019 …

Although our skin is not the primary visual organ in humans, it acts as a light sensor, playing
a significant role in maintaining our health and overall well-being. Thanks to the presence of …

Asthma demonstrates a strong circadian rhythm with disrupted molecular clock. Melatonin
which can directly regulate circadian rhythm has been reported to alleviate asthma, but …

内源性褪黑素是以色氨酸为原料, 经5-羟色胺(5-hydroxytryptamine) 途径合成,
从生物化学的角度来看, 研究人员认为内源性褪黑素是一种吲哚胺, 因为褪黑素分子含有一个被 …

褪黑素(melatonin) 是由松果体分泌的激素之一, 其调控昼夜节律和改善睡眠的功效已被广泛
研究和证实. 已有研究认为褪黑素过量或分泌紊乱能导致不良的健康效应. 近年来 …