[HTML][HTML] Epidemiology and burden of human papillomavirus and related diseases, molecular pathogenesis, and vaccine evaluation

AJ Kombe Kombe, B Li, A Zahid, HM Mengist… - Frontiers in public …, 2021 - frontiersin.org
Diagnosed in more than 90% of cervical cancers, the fourth deadliest cancer in women,
human papillomavirus (HPV) is currently the most common pathogen responsible for female …

Human papillomavirus infection and cervical cancer: epidemiology, screening, and vaccination—review of current perspectives

CK Chan, G Aimagambetova, T Ukybassova… - Journal of …, 2019 - Wiley Online Library
Viral infections contribute as a cause of 15–20% of all human cancers. Infection by
oncogenic viruses can promote different stages of carcinogenesis. Among many types of …

[HTML][HTML] Mechanistic role of HPV-associated early proteins in cervical cancer: Molecular pathways and targeted therapeutic strategies

R Bhattacharjee, SS Das, SS Biswal, A Nath… - Critical reviews in …, 2022 - Elsevier
Purpose Cervical cancer (CC), one of the major causes of death of women throughout the
world is primarily caused due to Human Papilloma Virus (HPV) 16 and 18. The early region …

[HTML][HTML] Human papillomaviruses as infectious agents in gynecological cancers. Oncogenic properties of viral proteins

DA Haręża, JR Wilczyński, E Paradowska - International journal of …, 2022 - mdpi.com
Human papillomaviruses (HPVs), which belong to the Papillomaviridae family, constitute a
group of small nonenveloped double-stranded DNA viruses. HPV has a small genome that …

p53 as a target for the treatment of cancer

MJ Duffy, NC Synnott, PM McGowan, J Crown… - Cancer treatment …, 2014 - Elsevier
Abstract TP53 (p53) is the most frequently mutated gene in cancer, being altered in
approximately 50% of human malignancies. In most, if not all, cancers lacking mutation, wild …

Hormonal contraceptives: pharmacology tailored to women's health

V De Leo, MC Musacchio, V Cappelli… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND In recent years, several new oral contraceptives have become available. In
some ways, they represent an evolution in terms of individualization and compliance on the …

[HTML][HTML] Effect of human papillomavirus infection on the immune system and its role in the course of cervical cancer

D Song, H Li, H Li, J Dai - Oncology letters, 2015 - spandidos-publications.com
Human papillomavirus (HPV) is widely known as a cause of cervical intraepithelial
neoplasia (CIN) and cervical cancer. The mechanisms involved have been studied by …

[HTML][HTML] Microbes and cancer: friends or faux?

MM Azevedo, C Pina-Vaz, F Baltazar - International journal of molecular …, 2020 - mdpi.com
Cancer is one of the most aggressive and deadly diseases in the world, representing the
second leading cause of death. It is a multifactorial disease, in which genetic alterations play …

Human papillomavirus community in healthy persons, defined by metagenomics analysis of human microbiome project shotgun sequencing data sets

Y Ma, R Madupu, U Karaoz, CW Nossa, L Yang… - Journal of …, 2014 - Am Soc Microbiol
Human papillomavirus (HPV) causes a number of neoplastic diseases in humans. Here, we
show a complex normal HPV community in a cohort of 103 healthy human subjects, by …

Gut microbiota and gynecological cancers: a summary of pathogenetic mechanisms and future directions

F Borella, AR Carosso, S Cosma, M Preti… - ACS Infectious …, 2021 - ACS Publications
Over the past 20 years, important relationships between the microbiota and human health
have emerged. A link between alterations of microbiota composition (dysbiosis) and cancer …