Lipid nanoparticles as delivery vehicles for inhaled therapeutics
EWX Leong, R Ge - Biomedicines, 2022 - mdpi.com
Lipid nanoparticles (LNPs) have emerged as a powerful non-viral carrier for drug delivery.
With the prevalence of respiratory diseases, particularly highlighted by the current COVID-19 …
With the prevalence of respiratory diseases, particularly highlighted by the current COVID-19 …
Targeting aging pathways in chronic obstructive pulmonary disease
M Easter, S Bollenbecker, JW Barnes… - International journal of …, 2020 - mdpi.com
Chronic obstructive pulmonary disease (COPD) has become a global epidemic and is the
third leading cause of death worldwide. COPD is characterized by chronic airway …
third leading cause of death worldwide. COPD is characterized by chronic airway …
FLIGHT1 and FLIGHT2: efficacy and safety of QVA149 (indacaterol/glycopyrrolate) versus its monocomponents and placebo in patients with chronic obstructive …
DA Mahler, E Kerwin, T Ayers… - American journal of …, 2015 - atsjournals.org
Rationale: Current Global Initiative for Chronic Obstructive Lung Disease (GOLD) strategy
recommends the combination of two long-acting bronchodilators of different pharmacologic …
recommends the combination of two long-acting bronchodilators of different pharmacologic …
Targeting cytokines as evolving treatment strategies in chronic inflammatory airway diseases
J Garth, JW Barnes, S Krick - International journal of molecular sciences, 2018 - mdpi.com
Cytokines are key players in the initiation and propagation of inflammation in chronic
inflammatory airway diseases such as chronic obstructive pulmonary disease (COPD) …
inflammatory airway diseases such as chronic obstructive pulmonary disease (COPD) …
β2‐adrenoceptor agonists: current and future direction
M Cazzola, L Calzetta… - British journal of …, 2011 - Wiley Online Library
Despite the passionate debate over the use of β2‐adrenoceptor agonists in the treatment of
airway disorders, these agents are still central in the symptomatic management of asthma …
airway disorders, these agents are still central in the symptomatic management of asthma …
How do dual long-acting bronchodilators prevent exacerbations of chronic obstructive pulmonary disease?
KM Beeh, PR Burgel, FME Franssen… - American journal of …, 2017 - atsjournals.org
Decreasing the frequency and severity of exacerbations is one of the main goals of
treatment for patients with chronic obstructive pulmonary disease. Several studies have …
treatment for patients with chronic obstructive pulmonary disease. Several studies have …
[HTML][HTML] Long-acting inhaled medicines: present and future
C Zhang, D D'Angelo, F Buttini, M Yang - Advanced Drug Delivery Reviews, 2023 - Elsevier
Inhaled medicines continue to be an essential part of treatment for respiratory diseases such
as asthma, chronic obstructive pulmonary disease, and cystic fibrosis. In addition, inhalation …
as asthma, chronic obstructive pulmonary disease, and cystic fibrosis. In addition, inhalation …
The complex association between COPD and COVID-19
Chronic obstructive pulmonary disease (COPD) is significant cause of morbidity and
mortality worldwide. There is mounting evidence suggesting that COPD patients are at …
mortality worldwide. There is mounting evidence suggesting that COPD patients are at …
Health-related quality of life and its associated factors in patients with chronic obstructive pulmonary disease
Objective The present study aimed to evaluate HRQOL and to explore the factors associated
with poor HRQOL among patients with COPD. Methods In the present cross-sectional study …
with poor HRQOL among patients with COPD. Methods In the present cross-sectional study …
Salmeterol Xinafoate (SX) loaded into mucoadhesive solid lipid microparticles for COPD treatment
E Amore, ML Manca, M Ferraro, D Valenti… - International Journal of …, 2019 - Elsevier
Chronic obstructive pulmonary disease (COPD) is one of the main health problems
worldwide. It is characterised by chronic inflammation in the lungs that leads to progressive …
worldwide. It is characterised by chronic inflammation in the lungs that leads to progressive …