JCM | Free Full-Text | Pediatric Acute Myeloid Leukemia—Past, Present, and Future Next
Article in Journal Sexual Habits and Sexual Dysfunctions in a Sample of Patients with Psychotic …

Although outcomes of children and adolescents with newly diagnosed acute myeloid
leukemia (AML) have improved significantly over the past two decades, more than one-third …

A hallmark of acute myeloid leukaemias (AMLs) are chromosomal rearrangements that give
rise to novel leukaemia-specific fusion genes. Most of these fusion genes are both initiating …

Survival outcomes for relapsed/refractory pediatric acute myeloid leukemia (R/R AML)
remain dismal. Epigenetic changes can result in gene expression alterations which are …

Simple Summary Pediatric patients with relapsed or refractory acute myeloid leukemia
(AML) have poor survival with current therapy. Venetoclax is a small molecule inhibitor that …

The great clinical success of chimeric antigen receptor (CAR) T cells has unlocked new
levels of immunotherapy for hematological malignancies. Genetically modifying natural killer …

Venetoclax is a strongly effective B-cell lymphoma-2 inhibitor (BCL-2) with an ability to
selectively restore the apoptotic potential of cancerous cells. It has been proven that in …

New methods like panel-based RNA fusion sequencing (RNA-FS) promise improved
diagnostics in various malignancies. We here analyzed the impact of RNA-FS on the initial …

Despite the maximum intensification of chemotherapy and the increased use of
hematopoietic stem cell transplantation (HCT) in pediatric patients with acute myeloid …

Simple Summary Acute myeloid leukemia (AML) is the second most frequent leukemia entity
in children and adolescents, and definitely the most aggressive variant. Multiparameter flow …