Karyotype complexity has major prognostic value in many malignancies. There is no
consensus on the definition of a complex karyotype, and the prognostic impact of karyotype …

Chromosome banding analysis (CBA) remains the standard-of-care for structural variant
(SV) assessment in MDS. Optical genome mapping (OGM) is a novel, non-sequencing …

Optical genome mapping (OGM) is a new genome-wide technology that can reveal both
structural genomic variations (SVs) and copy number variations (CNVs) in a single assay …

Cytogenetics has long represented a critical component in the clinical evaluation of
hematologic malignancies. Chromosome banding studies provide a simultaneous snapshot …

Complex karyotype identified by chromosome-banding analysis has been shown to have
prognostic value in chronic lymphocytic leukemia (CLL). Genomic arrays offer high …

Chromosomal microarray technologies, including array comparative genomic hybridization
and single-nucleotide polymorphism array, are widely applied in the diagnostic evaluation …

The detection of acquired copy-number abnormalities (CNAs) and copy-neutral loss of
heterozygosity (CN-LOH) in neoplastic disorders by chromosomal microarray analysis …

Simple Summary Myelodysplastic/myeloproliferative neoplasms (MDS/MPN) are clonal
myeloid neoplasms characterized, at the time of their presentation, by the simultaneous …

Structural chromosomal variants [copy number variants (CNVs): losses/gains and structural
variants (SVs): inversions, balanced and unbalanced fusions/translocations] are important …

The overlap in clinical presentation and bone marrow features of acquired and inherited
causes of hypocellular marrow failure poses a significant diagnostic challenge in real case …