Transition from homeostatic to reactive matrix remodeling is a fundamental adaptive tissue
response to injury, inflammatory disease, fibrosis, and cancer. Alterations in architecture …

Danger‐associated molecular patterns (DAMPs) are host‐derived molecules that can
function to regulate the activation of pathogen recognition receptors (PRRs). These …

The localization of circulating leukocytes within inflamed tissues occurs as the result of
interactions with and migration across vascular endothelium, and is governed, in part, by the …

A ubiquitous cell adhesion receptor, CD44, preferentially binds hyaluronan, a poly-
saccharide macromolecule that is present in most extracellular matrices. Hyaluronan …

Hyaluronan is a hygroscopic glycosaminoglycan that contributes to both extracellular and
pericellular matrices. While the production of hyaluronan is essential for mammalian …

Radiation-induced pneumonitis and fibrosis are dose-limiting side effects of thoracic
irradiation. Thoracic irradiation triggers acute and chronic environmental lung changes that …

Gerdin B, Hällgren R (University Hospital, Uppsala, Sweden). Dynamic role of hyaluronan
(HYA) in connective tissue activation and inflammation (Minisymposium: Hyaluronan). J …

We recently found that low-molecular-weight hyaluronan was induced by cyclic stretch in
lung fibroblasts and accumulated in lungs from animals with ventilator-induced lung injury …

Pulmonary niche dynamically orchestrates the signals, such as proliferation or differentiation
of mesenchymal stem cells (MSCs), which allows inducing tissue repair. Lung niche …

The goals of this study were to characterize the changes in chondroitin sulfate proteoglycans
and hyaluronan in lungs in acute response to gram-negative bacterial infection and to …