Identification of the role of MCM6 in bladder cancer prognosis, immunotherapy response, and in vitro experimental investigation using multi-omics analysis
J Wang, X Li, S Chen, J Cao, X Fan, H Wang, X Zhang… - Life Sciences, 2023 - Elsevier
Background The tumor-promoting effects of MCM6 in numerous tumors have been widely
revealed, yet its specific role in bladder cancer (BLCA) is still elusive. The objective of this …
revealed, yet its specific role in bladder cancer (BLCA) is still elusive. The objective of this …
CD8+ Cell Density Gradient across the Tumor Epithelium–Stromal Interface of Non-Muscle Invasive Papillary Urothelial Carcinoma Predicts Recurrence-Free Survival …
J Drachneris, A Rasmusson, M Morkunas… - Cancers, 2023 - mdpi.com
Simple Summary Bacille Calmette–Guerin (BCG) immunotherapy of non-muscle invasive
papillary urothelial carcinoma fails in over 30% of cases. In our study, we explore the …
papillary urothelial carcinoma fails in over 30% of cases. In our study, we explore the …
An N6-methyladenosine regulation-and mRNAsi-related prognostic index reveals the distinct immune microenvironment and immunotherapy responses in lower …
G Tang, J Peng, L Huo, W Yin - BMC bioinformatics, 2023 - Springer
Abstract Background N6-methyladenosine (m6A) modification is involved in tumorigenesis
and progression as well as closely correlated with stem cell differentiation and pluripotency …
and progression as well as closely correlated with stem cell differentiation and pluripotency …
Prognosis and immune infiltration analysis of endoplasmic reticulum stress-related genes in bladder urothelial carcinoma
Y Wang, H Zhu, X Wang - Frontiers in Genetics, 2022 - frontiersin.org
Background: Abnormal activation of endoplasmic reticulum (ER) stress sensors and their
downstream signalling pathways is a key regulator of tumour growth, tumour metastasis and …
downstream signalling pathways is a key regulator of tumour growth, tumour metastasis and …
PD-1-positive tumor-associated macrophages define poor clinical outcomes in patients with muscle invasive bladder cancer through potential CD68/PD-1 complex …
LR Jiang, N Zhang, ST Chen, J He, YH Liu… - Frontiers in …, 2021 - frontiersin.org
Tumor-associated macrophages (TAMs) regulate tumor immunity. Previous studies have
shown that the programmed cell death protein 1 (PD-1)-positive TAMs have an M2 …
shown that the programmed cell death protein 1 (PD-1)-positive TAMs have an M2 …
Multi-cohort validation of Ascore: an anoikis-based prognostic signature for predicting disease progression and immunotherapy response in bladder cancer
T Xie, S Peng, S Liu, M Zheng, W Diao, M Ding, Y Fu… - Molecular Cancer, 2024 - Springer
Bladder cancer ranks as the 10th most common cancer worldwide, with deteriorating
prognosis as the disease advances. While immune checkpoint inhibitors (ICIs) have shown …
prognosis as the disease advances. While immune checkpoint inhibitors (ICIs) have shown …
[HTML][HTML] A novel 6-gene signature derived from tumor-infiltrating T cells and neutrophils predicts survival of bladder urothelial carcinoma
X Zou, Y Wei, T Qi, X Wang, W Zuo, T Wang… - Aging (albany …, 2021 - ncbi.nlm.nih.gov
Intratumoral immune cells were reported to be associated with prognosis of bladder
urothelial carcinoma (BUC). However, the role of immune cells related genes in BUC …
urothelial carcinoma (BUC). However, the role of immune cells related genes in BUC …
The emerging role of thymopoietin-antisense RNA 1 as long noncoding RNA in the pathogenesis of human cancers
Q Zheng, J Jia, Z Zhou, Q Chu, W Lian… - DNA and Cell …, 2021 - liebertpub.com
Long noncoding RNAs (lncRNAs) play essential roles in the occurrence and development of
multiple human cancers. An accumulating body of researches have investigated …
multiple human cancers. An accumulating body of researches have investigated …
Expression of ferroptosis-related gene correlates with immune microenvironment and predicts prognosis in gastric cancer
S Song, P Shu - Scientific Reports, 2022 - nature.com
The study is to explore the role of ferroptosis-related genes (FRGs) in the occurrence and
development of gastric cancer (GC), and to construct a new prognosis signature to predict …
development of gastric cancer (GC), and to construct a new prognosis signature to predict …
Clinical utility of checkpoint inhibitors against metastatic bladder cancer: overcoming challenges to find a way forward
A Bilé-Silva, A Lopez-Beltran, A Blanca… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Cisplatin-based chemotherapy is currently considered the gold-standard
treatment for metastatic urothelial carcinoma (mUC). Nevertheless, most mUC patients …
treatment for metastatic urothelial carcinoma (mUC). Nevertheless, most mUC patients …