The proteome, or collection of proteoforms expressed in a biological system, is dynamic and
heterogeneous. As our appreciation for the complexity of the proteome has evolved, so have …

The emergence of cultured meat presents the potential for personalized food additive
manufacturing, offering a solution to address future food resource scarcity. Processing raw …

Improving coverage, robustness, and sensitivity is crucial for routine phosphoproteomics
analysis by single-shot liquid chromatography-tandem mass spectrometry (LC-MS/MS) from …

Mass spectrometry (MS)-based proteomics aims to characterize comprehensive proteomes
in a fast and reproducible manner. Here we present the narrow-window data-independent …

Detection of endogenous peptides, especially those with modifications (such as
phosphorylation) in biofluids, can serve as an indicator of intracellular pathophysiology …

Colorectal cancer (CRC) contains considerable heterogeneity; therefore, models of the
disease must also reflect the multifarious components. Compared to traditional 2D models …

Data-independent acquisition (DIA) has become a well-established method for MS-based
proteomics. However, the list of options to analyze this type of data is quite extensive, and …

With significant advances in analytical technologies, research in the field of cancer
immunotherapy, such as adoptive T cell therapy, cancer vaccine, and immune checkpoint …

Data-independent acquisition (DIA) mass spectrometry (MS) has emerged as a powerful
technology for high-throughput, accurate, and reproducible quantitative proteomics. This …

Tandem mass tags data-dependent acquisition (TMT-DDA) as well as data-independent
acquisition-based label-free quantification (LFQ-DIA) have become the leading workflows to …