Microbiome and human health: current understanding, engineering, and enabling technologies
The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …
Recent advances in butanol production by acetone-butanol-ethanol (ABE) fermentation
Butanol can be produced from renewable sources via the acetone-butanol-ethanol (ABE)
fermentation route to create biobutanol or from fossil fuel to create petrobutanol. Despite the …
fermentation route to create biobutanol or from fossil fuel to create petrobutanol. Despite the …
A metabolic pathway for bile acid dehydroxylation by the gut microbiome
M Funabashi, TL Grove, M Wang, Y Varma… - Nature, 2020 - nature.com
The gut microbiota synthesize hundreds of molecules, many of which influence host
physiology. Among the most abundant metabolites are the secondary bile acids deoxycholic …
physiology. Among the most abundant metabolites are the secondary bile acids deoxycholic …
Application of different types of CRISPR/Cas-based systems in bacteria
Z Liu, H Dong, Y Cui, L Cong, D Zhang - Microbial cell factories, 2020 - Springer
As important genome editing tools, CRISPR/Cas systems, especially those based on type II
Cas9 and type V Cas12a, are widely used in genetic and metabolic engineering of bacteria …
Cas9 and type V Cas12a, are widely used in genetic and metabolic engineering of bacteria …
Editing of the Bacillus subtilis genome by the CRISPR-Cas9 system
J Altenbuchner - Applied and environmental microbiology, 2016 - Am Soc Microbiol
The clustered regularly interspaced short palindromic repeat (CRISPR)-associated (Cas)
systems are adaptive immune systems of bacteria. A type II CRISPR-Cas9 system from …
systems are adaptive immune systems of bacteria. A type II CRISPR-Cas9 system from …
Exploiting endogenous CRISPR-Cas system for multiplex genome editing in Clostridium tyrobutyricum and engineer the strain for high-level butanol production
Abstract Although CRISPR-Cas9/Cpf1 have been employed as powerful genome
engineering tools, heterologous CRISPR-Cas9/Cpf1 are often difficult to introduce into …
engineering tools, heterologous CRISPR-Cas9/Cpf1 are often difficult to introduce into …
Advances in industrial biotechnology using CRISPR-Cas systems
PD Donohoue, R Barrangou, AP May - Trends in biotechnology, 2018 - cell.com
The term 'clustered regularly interspaced short palindromic repeats'(CRISPR) has recently
become synonymous with the genome-editing revolution. The RNA-guided endonuclease …
become synonymous with the genome-editing revolution. The RNA-guided endonuclease …
Recent advances and state-of-the-art strategies in strain and process engineering for biobutanol production by Clostridium acetobutylicum
Butanol as an advanced biofuel has gained great attention due to its environmental benefits
and superior properties compared to ethanol. However, the cost of biobutanol production via …
and superior properties compared to ethanol. However, the cost of biobutanol production via …
CRISPR Cpf1 proteins: structure, function and implications for genome editing
F Safari, K Zare, M Negahdaripour… - Cell & bioscience, 2019 - Springer
CRISPR and CRISPR-associated (Cas) protein, as components of microbial adaptive
immune system, allows biologists to edit genomic DNA in a precise and specific way …
immune system, allows biologists to edit genomic DNA in a precise and specific way …
Applications of CRISPR/Cas system to bacterial metabolic engineering
The clustered regularly interspaced short palindromic repeats/CRISPR-associated
(CRISPR/Cas) adaptive immune system has been extensively used for gene editing …
(CRISPR/Cas) adaptive immune system has been extensively used for gene editing …