The different types of striatal neuron show a range of vulnerabilities to a variety of insults.
This can be clearly seen in Huntington's disease where a well mapped pattern of …

Written for practitioners in the field, this critically acclaimed bestseller provides authoritative
information focused on the investigation of drug-related deaths and practical approaches to …

Advances in research on globus pallidus (GP) suggest that this 'long thought to be'relay in
the 'indirect pathway'plays a unique and critical role in basal ganglia function. The traditional …

Dysfunction of N-Methyl-d-aspartate receptors (NMDARs) is believed to underlie some of the
symptoms in schizophrenia, and non-competitive NMDAR antagonists (including …

Dextromethorphan, an antitussive widely available over-the-counter, is abused, mostly by
teenagers at high doses. In our previous report, a high dose of dextromethorphan activated …

Phencyclidine (PCP) has recently been shown to induce apoptosis of a subpopulation of
striatopallidal neurons which lie in the dorsomedial caudate–putamen. The pharmacological …

N-methyl-d-aspartate receptor antagonism exerts suppressive influences over dopamine D1
receptor-mediated striatal gene expression and locomotor behavior in the intact rat. The …

Specific neurons in the brain are the primary targets of the action of antipsychotic drugs.
Identification and characterization of the nature of these neurons are important for …