Common variable immunodeficiency: epidemiology, pathogenesis, clinical manifestations, diagnosis, classification, and management.

R Yazdani, S Habibi, L Sharifi, G Azizi… - … allergology & clinical …, 2019 - europepmc.org
Common variable immunodeficiency (CVID) is a heterogeneous disorder characterized by
hypogammaglobulinemia and increased susceptibility to recurrent bacterial infections. It is …

Autoimmunity in common variable immunodeficiency: epidemiology, pathophysiology and management

G Azizi, H Abolhassani, MH Asgardoon… - Expert review of …, 2017 - Taylor & Francis
Introduction: Common variable immunodeficiency (CVID) comprises a large heterogeneous
group of patients with primary antibody deficiency. Areas covered: The affected patients are …

Autoimmune cytopenias in common variable immunodeficiency are a diagnostic and therapeutic conundrum: an update

S Chawla, P Barman, R Tyagi, AK Jindal… - Frontiers in …, 2022 - frontiersin.org
Common variable immunodeficiency (CVID) is the most common symptomatic primary
immunodeficiency (PID). CVID is a heterogenous condition and clinical manifestations may …

Identification of novel genetic variants in CVID patients with autoimmunity, autoinflammation, or malignancy

M Christiansen, R Offersen, JMB Jensen… - Frontiers in …, 2020 - frontiersin.org
Common variable immunodeficiency (CVID) is a primary immunodeficiency characterized by
recurrent bacterial infections and defined by reduced levels of IgG, IgA, and/or IgM …

Identification and characterization of a nationwide Danish adult common variable immunodeficiency cohort

L Westh, TH Mogensen, LS Dalgaard… - Scandinavian …, 2017 - Wiley Online Library
In this study, we identified all adults living in Denmark diagnosed with common variable
immunodeficiency (CVID) and characterized them according to clinical presentation and …

Autoimmunity in primary antibody deficiencies

G Azizi, M Ahmadi, H Abolhassani, R Yazdani… - International archives of …, 2017 - karger.com
Primary antibody deficiencies (PADs) are the most common inherited primary
immunodeficiencies in humans, characterized by hypogammaglobulinemia, an inability to …

IL-10-producing regulatory B cells are decreased in patients with common variable immunodeficiency

NS Barsotti, RR Almeida, PR Costa, MT Barros, J Kalil… - PLoS …, 2016 - journals.plos.org
Common variable immunodeficiency (CVID) is the most prevalent symptomatic primary
immunodeficiency in adults. CVID patients often present changes in the frequency and …

Abnormality of regulatory T cells in common variable immunodeficiency

G Azizi, N Hafezi, H Mohammadi, R Yazdani, T Alinia… - Cellular …, 2017 - Elsevier
Common variable immunodeficiency (CVID) is a heterogeneous group of primary antibody
deficiencies (PAD) which is defined by recurrent infections, hypogammaglobulinemia and …

Members of the regulatory lymphocyte club in common variable immunodeficiency

S Gupta, Y Demirdag, AA Gupta - Frontiers in Immunology, 2022 - frontiersin.org
The role of CD4 T regulatory cells is well established in peripheral tolerance and the
pathogenesis of the murine model and human autoimmune diseases. CD4 T regulatory cells …

Patients with common variable immunodeficiency complicated by autoimmune phenomena have lymphopenia and reduced treg, Th17, and NK cells

E Więsik-Szewczyk, E Rutkowska, I Kwiecień… - Journal of Clinical …, 2021 - mdpi.com
Most patients with primary immune deficiency suffer from recurrent infections; however,
paradoxical autoimmune phenomena can also manifest. The aim of this study was to identify …