Age-associated differences in the cancer molecular landscape
Cancer is an age-related disease, as incidence and mortality for most types of cancer
increase with age. However, how molecular alterations in tumors differ among patients of …
increase with age. However, how molecular alterations in tumors differ among patients of …
Curcumin as prospective anti-aging natural compound: focus on brain
T Benameur, R Soleti, MA Panaro, ME La Torre… - Molecules, 2021 - mdpi.com
The nutrients and their potential benefits are a new field of study in modern medicine for
their positive impact on health. Curcumin, the yellow polyphenolic compound extracted from …
their positive impact on health. Curcumin, the yellow polyphenolic compound extracted from …
Clinical biomarker-based biological aging and risk of cancer in the UK Biobank
Background Despite a clear link between aging and cancer, there has been inconclusive
evidence on how biological age (BA) may be associated with cancer incidence. Methods We …
evidence on how biological age (BA) may be associated with cancer incidence. Methods We …
Effect of physical activity, smoking, and sleep on telomere length: a systematic review of observational and intervention studies
R Barragán, C Ortega-Azorín, JV Sorli… - Journal of clinical …, 2021 - mdpi.com
Aging is a risk factor for several pathologies, restricting one's health span, and promoting
chronic diseases (eg, cardiovascular and neurodegenerative diseases), as well as cancer …
chronic diseases (eg, cardiovascular and neurodegenerative diseases), as well as cancer …
Neural cell state shifts and fate loss in ageing and age-related diseases
Most age-related neurodegenerative diseases remain incurable owing to an incomplete
understanding of the disease mechanisms. Several environmental and genetic factors …
understanding of the disease mechanisms. Several environmental and genetic factors …
Estradiol as the trigger of sirtuin-1-dependent cell signaling with a potential utility in anti-aging therapies
K Karolczak, C Watala - International Journal of Molecular Sciences, 2023 - mdpi.com
Aging entails the inevitable loss of the structural and functional integrity of cells and tissues
during the lifetime. It is a highly hormone-dependent process; although, the exact …
during the lifetime. It is a highly hormone-dependent process; although, the exact …
Peroxiredoxin, senescence, and cancer
M Wu, C Deng, TH Lo, KY Chan, X Li, CM Wong - Cells, 2022 - mdpi.com
Peroxiredoxins are multifunctional enzymes that play a key role in protecting cells from
stresses and maintaining the homeostasis of many cellular processes. Peroxiredoxins were …
stresses and maintaining the homeostasis of many cellular processes. Peroxiredoxins were …
Effectiveness of geriatric assessment and management in older cancer patients: a systematic review and meta-analysis
Background Frailty and multimorbidity among older cancer patients affect treatment
tolerance and efficacy. Comprehensive geriatric assessment and management is …
tolerance and efficacy. Comprehensive geriatric assessment and management is …
[HTML][HTML] HSF1 Inhibits Antitumor Immune Activity in Breast Cancer by Suppressing CCL5 to Block CD8+ T-cell Recruitment
C Jacobs, S Shah, WC Lu, H Ray, J Wang… - Cancer Research, 2024 - AACR
Abstract Heat shock factor 1 (HSF1) is a stress-responsive transcription factor that promotes
cancer cell malignancy. To provide a better understanding of the biological processes …
cancer cell malignancy. To provide a better understanding of the biological processes …
Identification of senescence-related molecular subtypes and key genes for prostate cancer
DC Feng, WZ Zhu, X Shi, Q Xiong, J You… - Asian journal of …, 2023 - journals.lww.com
We identified distinct senescence-related molecular subtypes and critical genes among
prostate cancer (PCa) patients undergoing radical prostatectomy (RP) or radical …
prostate cancer (PCa) patients undergoing radical prostatectomy (RP) or radical …