Overview of the 2022 WHO classification of thyroid neoplasms

ZW Baloch, SL Asa, JA Barletta, RA Ghossein… - Endocrine …, 2022 - Springer
This review summarizes the changes in the 5th edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new …

Epidemiology of thyroid cancer

CM Kitahara, AB Schneider - Cancer epidemiology, biomarkers & prevention, 2022 - AACR
Background The incidence of thyroid cancer has risen dramatically in the United States over
the past four decades, with similar patterns observed internationally. Thyroid cancer …

Heterogeneity of thyroid cancer

E Chmielik, D Rusinek, M Oczko-Wojciechowska… - Pathobiology, 2018 - karger.com
There are 5 main histological types of thyroid cancers (TCs): papillary, follicular (also known
as differentiated), poorly differentiated, anaplastic (the most aggressive form), and medullary …

Thyroid carcinoma: phenotypic features, underlying biology and potential relevance for targeting therapy

J Hu, IJ Yuan, S Mirshahidi, A Simental, SC Lee… - International journal of …, 2021 - mdpi.com
Thyroid carcinoma consists a group of phenotypically heterogeneous cancers. Recent
advances in biological technologies have been advancing the delineation of genetic …

Whole‐genome sequencing of synchronous thyroid carcinomas identifies aberrant DNA repair in thyroid cancer dedifferentiation

JO Paulsson, S Backman, N Wang… - The Journal of …, 2020 - Wiley Online Library
The genetics underlying thyroid cancer dedifferentiation is only partly understood and has
not yet been characterised using comprehensive pan‐genomic analyses. We investigated a …

Pitfalls in thyroid cytopathology

ED Rossi, AJ Adeniran… - Surgical pathology …, 2019 - surgpath.theclinics.com
Fine-needle aspiration (FNA) is among the first diagnostic tools used in the evaluation of
thyroid nodules. It has the ability to triage patients with benign and malignant lesions, thus …

Prognostic classification of thyroid follicular cell tumors using Ki-67 labeling index: risk stratification of thyroid follicular cell carcinomas

K Kakudo, T Wakasa, Y Ohta, K Yane, Y Ito… - Endocrine …, 2015 - jstage.jst.go.jp
This review emphasizes that the so-called high-risk thyroid carcinoma is not a distinct tumor
entity, but a group of tumors with different histologies. High-grade histological features, such …

Cytologic features of aggressive variants of follicular‐derived thyroid carcinoma

ED Rossi, WC Faquin, L Pantanowitz - Cancer cytopathology, 2019 - Wiley Online Library
Certain carcinomas of the thyroid gland behave aggressively resulting in increased patient
morbidity and poor patient prognosis. The diagnosis of these aggressive thyroid cancer …

Effects and role of multikinase inhibitors in thyroid cancer

R Laursen, M Wehland, S Kopp… - Current …, 2016 - ingentaconnect.com
Background: Thyroid cancer is the most common type of endocrine neoplasia. Differentiated
thyroid carcinoma (DTC) represents 94% of all thyroid cancer types. Approximately 20 …

Tall cell percentage alone in PTC without aggressive features should not guide patients' clinical management

AM Poma, D Viola, E Macerola, A Proietti… - The Journal of …, 2021 - academic.oup.com
Context Recent diagnostic criteria updates of the tall cell variant of papillary thyroid
carcinoma (TCPTC) by the World Health Organization (WHO) have determined the inclusion …