Visualizing and perturbing neural activity on a brain-wide scale in model animals and
humans is a major goal of neuroscience technology development. Established electrical and …

Because it drives the compromise between resolution and penetration, the diffraction limit
has long represented an unreachable summit to conquer in ultrasound imaging. Within a …

Abstract Changes in cerebral blood flow are associated with stroke, aneurysms, vascular
cognitive impairment, neurodegenerative diseases and other pathologies. Brain …

Non-invasive imaging deep into organs at microscopic scales remains an open quest in
biomedical imaging. Although optical microscopy is still limited to surface imaging owing to …

Efforts to scale neuroimaging towards the direct visualization of mammalian brain-wide
neuronal activity have faced major challenges. Although high-resolution optical imaging of …

We extended the capabilities of functional ultrasound to whole-brain four-dimensional (4D)
neuroimaging. Our multiplane-wave transmission scheme on matrix arrays at thousands of …

Recent advances in ultrasound (US) have shown its great potential in biomedical
applications as diagnostic and therapeutic tools. The coupling of US-assisted drug delivery …

Super-resolution ultrasound microvessel imaging with contrast microbubbles has recently
been proposed by multiple studies, demonstrating outstanding resolution with high potential …

Contrast enhanced ultrasound is a radiation-free imaging modality which uses encapsulated
gas microbubbles for improved visualization of the vascular bed deep within the tissue. It …

Ultrasound sensitivity to slow blood flow motion gained two orders of magnitude in the last
decade thanks to the advent of ultrafast ultrasound imaging at thousands of frames per …