Components of the neurovascular unit (NVU) establish dynamic crosstalk that regulates
cerebral blood flow and maintain brain homeostasis. Here, we describe accumulating …

The brain is a highly metabolically active organ requiring a large amount of glucose.
Methylglyoxal (MGO), a by-product of glucose metabolism, is known to be involved in …

SARS-CoV-2 causes COVID-19, which has claimed millions of lives. This virus can infect
various cells and tissues, including the brain, for which numerous neurological symptoms …

People living with chronic kidney disease (CKD) frequently suffer from mild cognitive
impairment and/or other neurocognitive disorders. This review in two parts will focus on …

Central nervous system (CNS) injuries are the most common cause of death and disability
around the world. The blood-brain barrier (BBB) is located at the interface between the CNS …

The blood–brain barrier (BBB) is pivotal in maintaining neuronal physiology within the brain.
This review delves into the alterations of the BBB specifically in the context of geriatric …

Patients with chronic kidney disease (CKD) have an increased risk of both ischaemic and
haemorrhagic stroke compared with the general population. Both acute and chronic kidney …

Glioblastoma (GBM) is the most malignant form of all primary brain tumors, and it is
responsible for around 200,000 deaths each year worldwide. The standard therapy for GBM …

Hypertension in midlife contributes to cognitive decline and is a modifiable risk factor for
dementia. The relationship between late-life hypertension and dementia is less clear. We …

Abstract Purpose of Review The incidence of hypertensive disorders of pregnancy (HDP),
especially preeclampsia has increased significantly over the last two decades. Patients with …