Recently, electrospun polymeric nanofibers have proven to be an interesting strategy for
drug delivery systems application. The high surface-to-volume ratio of the fibers can improve …

The development of oral dosage forms for poorly water-soluble active pharmaceutical
ingredients (APIs) is a persistent challenge. A range of methods has been explored to …

The limitations of conventional therapeutic drugs necessitate the importance of developing
novel therapeutics to treat diverse diseases. Conventional drugs have poor blood circulation …

Electrospinning has emerged as most viable approach for the fabrication of nanofibers with
several beneficial features that are essential to various applications ranging from …

Electrospinning is a technique to generate fibrous structures through elongation of electrified
jets with an external electric field. Its versatility produces fibres that are being utilised in a …

Acyclovir is an effective antiviral drug which suffers from limited water solubility and low
bioavailability. However, it is possible to eliminate these limitations by forming inclusion …

Electrospun nanofibers have sparked tremendous attention in drug delivery since they can
offer high specific surface area, tailored release of drugs, controlled surface chemistry for …

Improving the oral absorption of compounds with low aqueous solubility is a common
challenge that often requires an enabling technology. Frequently, oral absorption can be …

Replacing in vivo with in vitro studies can increase sustainability in the development of
medicines. This principle has already been applied in the biowaiver approach based on the …

The aim of this study was to investigate the impact of formulation excipients and solubilizing
additives on dissolution, supersaturation, and membrane transport of an active …