A summary of electrospun nanofibers as drug delivery system: Drugs loaded and biopolymers used as matrices
EJ Torres-Martínez, JM Cornejo Bravo… - Current drug …, 2018 - ingentaconnect.com
Recently, electrospun polymeric nanofibers have proven to be an interesting strategy for
drug delivery systems application. The high surface-to-volume ratio of the fibers can improve …
drug delivery systems application. The high surface-to-volume ratio of the fibers can improve …
Electrospun amorphous solid dispersions of poorly water-soluble drugs: A review
DG Yu, JJ Li, GR Williams, M Zhao - Journal of controlled release, 2018 - Elsevier
The development of oral dosage forms for poorly water-soluble active pharmaceutical
ingredients (APIs) is a persistent challenge. A range of methods has been explored to …
ingredients (APIs) is a persistent challenge. A range of methods has been explored to …
Electrospinning nanofibers for therapeutics delivery
The limitations of conventional therapeutic drugs necessitate the importance of developing
novel therapeutics to treat diverse diseases. Conventional drugs have poor blood circulation …
novel therapeutics to treat diverse diseases. Conventional drugs have poor blood circulation …
Progress in the design and development of “fast-dissolving” electrospun nanofibers based drug delivery systems-A systematic review
Electrospinning has emerged as most viable approach for the fabrication of nanofibers with
several beneficial features that are essential to various applications ranging from …
several beneficial features that are essential to various applications ranging from …
Electrospinning and its potential in fabricating pharmaceutical dosage form
Electrospinning is a technique to generate fibrous structures through elongation of electrified
jets with an external electric field. Its versatility produces fibres that are being utilised in a …
jets with an external electric field. Its versatility produces fibres that are being utilised in a …
Electrospun formulation of acyclovir/cyclodextrin nanofibers for fast-dissolving antiviral drug delivery
A Celebioglu, T Uyar - Materials Science and Engineering: C, 2021 - Elsevier
Acyclovir is an effective antiviral drug which suffers from limited water solubility and low
bioavailability. However, it is possible to eliminate these limitations by forming inclusion …
bioavailability. However, it is possible to eliminate these limitations by forming inclusion …
Electrospinning of cyclodextrin functional nanofibers for drug delivery applications
F Topuz, T Uyar - Pharmaceutics, 2018 - mdpi.com
Electrospun nanofibers have sparked tremendous attention in drug delivery since they can
offer high specific surface area, tailored release of drugs, controlled surface chemistry for …
offer high specific surface area, tailored release of drugs, controlled surface chemistry for …
Impact of Drug-Rich Colloids of Itraconazole and HPMCAS on Membrane Flux in Vitro and Oral Bioavailability in Rats
AM Stewart, ME Grass, TJ Brodeur… - Molecular …, 2017 - ACS Publications
Improving the oral absorption of compounds with low aqueous solubility is a common
challenge that often requires an enabling technology. Frequently, oral absorption can be …
challenge that often requires an enabling technology. Frequently, oral absorption can be …
[HTML][HTML] Commercially available cell-free permeability tests for industrial drug development: increased sustainability through reduction of in vivo studies
AC Jacobsen, S Visentin, C Butnarasu, PC Stein… - Pharmaceutics, 2023 - mdpi.com
Replacing in vivo with in vitro studies can increase sustainability in the development of
medicines. This principle has already been applied in the biowaiver approach based on the …
medicines. This principle has already been applied in the biowaiver approach based on the …
Investigation and mathematical description of the real driving force of passive transport of drug molecules from supersaturated solutions
The aim of this study was to investigate the impact of formulation excipients and solubilizing
additives on dissolution, supersaturation, and membrane transport of an active …
additives on dissolution, supersaturation, and membrane transport of an active …