Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions

C Qin, S Yang, YH Chu, H Zhang, XW Pang… - Signal transduction and …, 2022 - nature.com
Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …

[HTML][HTML] Therapeutic targets of neuroprotection and neurorestoration in ischemic stroke: Applications for natural compounds from medicinal herbs

T Zhu, L Wang, L Wang, Q Wan - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Neuroprotective and neurorestorative therapy represent two major drug intervention
strategies for ischemic stroke. Multiple factors such as excitotoxicity, inflammation …

Crosstalk between the oxidative stress and glia cells after stroke: from mechanism to therapies

G Zhu, X Wang, L Chen, C Lenahan, Z Fu… - Frontiers in …, 2022 - frontiersin.org
Stroke is the second leading cause of global death and is characterized by high rates of
mortality and disability. Oxidative stress is accompanied by other pathological processes …

Prognostic value of neutrophil-to-lymphocyte ratio in stroke: a systematic review and meta-analysis

W Li, M Hou, Z Ding, X Liu, Y Shao, X Li - Frontiers in Neurology, 2021 - frontiersin.org
Background: Stroke has become a major problem around the world, which is one of the
main causes of long-term disability. Therefore, it is important to seek a biomarker to predict …

Role of ferroptosis in stroke

Y Xu, K Li, Y Zhao, L Zhou, Y Liu, J Zhao - Cellular and Molecular …, 2023 - Springer
Stroke is a common and serious nervous system disease caused by the rupture or blockage
of the cardiovascular system. It causes millions of deaths and disabilities every year, which …

Insight into crosstalk between ferroptosis and necroptosis: novel therapeutics in ischemic stroke

Y Zhou, J Liao, Z Mei, X Liu, J Ge - Oxidative Medicine and …, 2021 - Wiley Online Library
Ferroptosis is a nonapoptotic form of cell death characterized by iron‐dependent
accumulation of lipid hydroperoxides to lethal levels. Necroptosis, an alternative form of …

Impact of nanoparticles on brain health: an up to date overview

DM Teleanu, C Chircov, AM Grumezescu… - Journal of clinical …, 2018 - mdpi.com
Nanoparticles are zero-dimensional nanomaterials and, based on their nature, they can be
categorized into organic, inorganic, and composites nanoparticles. Due to their unique …

Nanoparticles in the diagnosis and treatment of vascular aging and related diseases

H Xu, S Li, YS Liu - Signal Transduction and Targeted Therapy, 2022 - nature.com
Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …

[HTML][HTML] The mechanism of ferroptosis regulating oxidative stress in ischemic stroke and the regulation mechanism of natural pharmacological active components

K Yang, L Zeng, X Yuan, S Wang, A Ge, H Xu… - Biomedicine & …, 2022 - Elsevier
Cerebrovascular diseases, such as ischemic stroke, pose serious medical challenges
worldwide due to their high morbidity and mortality and limitations in clinical treatment …

Prussian blue nanozymes: progress, challenges, and opportunities

H He, M Long, Y Duan, N Gu - Nanoscale, 2023 - pubs.rsc.org
Prussian Blue Nanozymes (PBNZs) have emerged as highly efficient agents for reactive
oxygen species (ROS) elimination, owing to their multiple enzyme-like properties …