[HTML][HTML] Natural polysaccharides for siRNA delivery: Nanocarriers based on chitosan, hyaluronic acid, and their derivatives
I Serrano-Sevilla, Á Artiga, SG Mitchell, L De Matteis… - Molecules, 2019 - mdpi.com
Natural polysaccharides are frequently used in the design of drug delivery systems due to
their biocompatibility, biodegradability, and low toxicity. Moreover, they are diverse in …
their biocompatibility, biodegradability, and low toxicity. Moreover, they are diverse in …
[HTML][HTML] Multifaceted applications of chitosan in cancer drug delivery and therapy
Chitosan is a versatile polysaccharide of biological origin. Due to the biocompatible and
biodegradable nature of chitosan, it is intensively utilized in biomedical applications in …
biodegradable nature of chitosan, it is intensively utilized in biomedical applications in …
[HTML][HTML] Chitosan-based nanoparticles for nucleic acid delivery: technological aspects, applications, and future perspectives
Chitosan is a naturally occurring polymer derived from the deacetylation of chitin, which is
an abundant carbohydrate found mainly in the shells of various marine and terrestrial …
an abundant carbohydrate found mainly in the shells of various marine and terrestrial …
Nanodelivery of resveratrol-loaded PLGA nanoparticles for age-related macular degeneration
P Bhatt, G Fnu, D Bhatia, A Shahid, V Sutariya - AAPS PharmSciTech, 2020 - Springer
Age-related macular degeneration, precisely neovascular form, is the leading cause of
vision loss and the key treatment includes intravitreal injections of anti-vascular endothelial …
vision loss and the key treatment includes intravitreal injections of anti-vascular endothelial …
Production of low molecular weight chitosan by acid and oxidative pathways: Effect on physicochemical properties
BS de Farias, DDR Grundmann, FZ Rizzi… - Food Research …, 2019 - Elsevier
Chitosan–based biomaterials with a low molecular weight (LMW) have been drawn attention
due to the promising applications in the pharmaceutical and food fields. For this reason, the …
due to the promising applications in the pharmaceutical and food fields. For this reason, the …
An in vitro Assessment of Thermo-Reversible Gel Formulation Containing Sunitinib Nanoparticles for Neovascular Age-Related Macular Degeneration
P Bhatt, P Narvekar, R Lalani, MB Chougule… - AAPS …, 2019 - Springer
Anti-vascular endothelial growth factor agents have been widely used to treat several eye
diseases including age-related macular degeneration (AMD). An approach to maximize the …
diseases including age-related macular degeneration (AMD). An approach to maximize the …
Lipid-nucleic acid nanoparticles of novel ionizable lipids for systemic BMP-9 gene delivery to bone-marrow mesenchymal stem cells for osteoinduction
Rational design of novel ionizable lipids for development of lipid-nucleic acid nanoparticles
(LNP) is required for safe and effective systemic gene delivery for osteoporosis. LNPs …
(LNP) is required for safe and effective systemic gene delivery for osteoporosis. LNPs …
Fabrication of aptamer-guided siRNA loaded lipopolyplexes for gene silencing of notch 1 in MDA-mb-231 triple negative breast cancer cell line
L Gharaibeh, W Alshaer, S Wehaibi, R Al Buqain… - Journal of Drug Delivery …, 2021 - Elsevier
Triple negative breast cancer is an aggressive type of cancer with limited therapeutic
options. Aptamer-functionalized liposomes to deliver short interference RNAs (siRNAs) offer …
options. Aptamer-functionalized liposomes to deliver short interference RNAs (siRNAs) offer …
Co-delivery of cisplatin and siRNA through hybrid nanocarrier platform for masking resistance to chemotherapy in lung cancer
The resistance of cancer cells to chemotherapy has presented a formidable challenge. The
current research aims at evaluating whether silencing of the cisplatin efflux promoter gene …
current research aims at evaluating whether silencing of the cisplatin efflux promoter gene …
Colloidally stable small unilamellar stearyl amine lipoplexes for effective BMP-9 gene delivery to stem cells for osteogenic differentiation
The biocompatibility of cationic liposomes has led to their clinical translation in gene delivery
and their application apart from cancer to cardiovascular diseases, osteoporosis, metabolic …
and their application apart from cancer to cardiovascular diseases, osteoporosis, metabolic …