New Antimicrobial Strategies to Treat Multi-Drug Resistant Infections Caused by Gram-Negatives in Cystic Fibrosis

VC Scoffone, G Barbieri, S Irudal, G Trespidi, S Buroni - Antibiotics, 2024 - mdpi.com
People with cystic fibrosis (CF) suffer from recurrent bacterial infections which induce
inflammation, lung tissue damage and failure of the respiratory system. Prolonged exposure …

Harmine acts as a quorum sensing inhibitor decreasing the virulence and antibiotic resistance of Pseudomonas aeruginosa

P Chen, J Qin, HK Su, L Du, Q Zeng - BMC Infectious Diseases, 2024 - Springer
Background As antimicrobial resistance (AMR) has become a global health crisis, new
strategies against AMR infection are urgently needed. Quorum sensing (QS), responsible for …

Antibiofilm and Antivirulence Properties of 6-Polyaminosteroid Derivatives against Antibiotic-Resistant Bacteria

D Vergoz, H Le, B Bernay, A Schaumann, M Barreau… - Antibiotics, 2023 - mdpi.com
The emergence of multi-drug resistant pathogens is a major public health problem, leading
us to rethink and innovate our bacterial control strategies. Here, we explore the antibiofilm …