(1) Background: Scleroderma (Sc) is a rare connective tissue disease classified as an
autoimmune disorder. The pathogenesis of this disease is not fully understood.(2) Methods …

Systemic sclerosis (SSc) is an autoimmune disease characterised by microvasculopathy,
immune dysregulation, and skin and visceral organ fibrosis. Every year novel insights into …

Systemic sclerosis (SSc) is a complex autoimmune disease characterized by heterogeneous
changes involving numerous organs and systems. The currently available data indicate that …

Objectives Limited cutaneous systemic sclerosis (lcSSc) is the largest subgroup of people
with SSc, but little is known about symptom experience from the patients' perspective. This …

Objectives To explore the prognostic value of subclinical cardiovascular (CV) imaging
measures and serum cardiac biomarkers in systemic sclerosis (SSc) for the development of …

Introduction Cardiac involvement is common in systemic sclerosis occurring in up to 80% of
patients. Primary myocardial dysfunction results from impairment of coronary microvascular …

Autoimmune diseases (ADs) encompass multisystem disorders, and cardiovascular
involvement is a well-known feature of autoimmune and inflammatory rheumatic conditions …

结缔组织病(Connective Tissue Disease, CTD) 是一大类与遗传, 免疫以及病毒感染等有一定
关系的多因性疾病, 可累及全身多系统, 多器官, 包括心脏. 心血管磁共振成像(Cardiovascular …

Objectives Nintedanib is an inhibitor of tyrosine kinases that has been shown to slow the
progression of interstitial lung disease (ILD), including ILD associated with SSc. The aim of …

Systemic sclerosis (SSc) is a multifaceted connective tissue disease whose aetiology
remains largely unknown. Autoimmunity is thought to play a pivotal role in the development …