Overview of OxLDL and its impact on cardiovascular health: focus on atherosclerosis
AV Poznyak, NG Nikiforov, AM Markin… - Frontiers in …, 2021 - frontiersin.org
Cardiovascular pathologies maintain the leading position in mortality worldwide.
Atherosclerosis is a chronic disease that can result in a variety of serious complications …
Atherosclerosis is a chronic disease that can result in a variety of serious complications …
Lipid peroxidation in atherosclerotic cardiovascular diseases
E Gianazza, M Brioschi… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Atherosclerotic cardiovascular diseases (ACVDs) continue to be a primary
cause of mortality worldwide in adults aged 35–70 years, occurring more often in countries …
cause of mortality worldwide in adults aged 35–70 years, occurring more often in countries …
Malondialdehyde as an important key factor of molecular mechanisms of vascular wall damage under heart diseases development
VZ Lankin, AK Tikhaze, AM Melkumyants - International Journal of …, 2022 - mdpi.com
This mini review is devoted to a specific issue: the role of malondialdehyde (MDA)—a
secondary product of free radical lipid peroxidation—in the molecular mechanisms of the …
secondary product of free radical lipid peroxidation—in the molecular mechanisms of the …
LncRNA ANRIL acts as a modular scaffold of WDR5 and HDAC3 complexes and promotes alteration of the vascular smooth muscle cell phenotype
C Zhang, S Ge, W Gong, J Xu, Z Guo, Z Liu, X Gao… - Cell death & …, 2020 - nature.com
Many studies have shown that long-noncoding RNA (lncRNA) is associated with
cardiovascular disease, but its molecular mechanism is still unclear. In this study, we …
cardiovascular disease, but its molecular mechanism is still unclear. In this study, we …
Involvement of LDL and ox-LDL in cancer development and its therapeutical potential
CF Deng, N Zhu, TJ Zhao, HF Li, J Gu, DF Liao… - Frontiers in …, 2022 - frontiersin.org
Lipid metabolism disorder is related to an increased risk of tumorigenesis and is involved in
the rapid growth of cancer cells as well as the formation of metastatic lesions …
the rapid growth of cancer cells as well as the formation of metastatic lesions …
The up‐to‐date pathophysiology of Kawasaki disease
T Hara, K Yamamura, Y Sakai - Clinical & translational …, 2021 - Wiley Online Library
Kawasaki disease (KD) is an acute systemic vasculitis of an unknown aetiology. A small
proportion of children exposed to severe acute respiratory syndrome coronavirus 2 (SARS …
proportion of children exposed to severe acute respiratory syndrome coronavirus 2 (SARS …
[HTML][HTML] Leonurine prevents atherosclerosis via promoting the expression of ABCA1 and ABCG1 in a Pparγ/Lxrα signaling pathway-dependent manner
T Jiang, K Ren, Q Chen, H Li, R Yao, H Hu… - Cellular Physiology and …, 2017 - karger.com
Background/Aims: Previous studies have demonstrated that leonurine, a unique alkaloid
compound of Herba leonuri, can exert anti-oxidative and anti-inflammatory effects on the …
compound of Herba leonuri, can exert anti-oxidative and anti-inflammatory effects on the …
PCSK9: a novel inflammation modulator in atherosclerosis?
ZH Tang, TH Li, J Peng, J Zheng, TT Li… - Journal of Cellular …, 2019 - Wiley Online Library
Proprotein convertase subtilisin/kexin 9 (PCSK9) is the ninth member of the secretory serine
protease family. It binds to low‐density lipoprotein receptor (LDLR) for endocytosis and …
protease family. It binds to low‐density lipoprotein receptor (LDLR) for endocytosis and …
Role of glutathione peroxidases and peroxiredoxins in free radical-induced pathologies
MG Shaparov, SV Gudkov, VZ Lankin… - Biochemistry (Moscow …, 2021 - Springer
In this review, we discuss the pathogenesis of some socially significant diseases associated
with the development of oxidative stress, such as atherosclerosis, diabetes, and radiation …
with the development of oxidative stress, such as atherosclerosis, diabetes, and radiation …
Dicarbonyl-dependent modification of LDL as a key factor of endothelial dysfunction and atherosclerotic vascular wall damage
VZ Lankin, AK Tikhaze, AM Melkumyants - Antioxidants, 2022 - mdpi.com
The review presents evidence that the main damage to the vascular wall occurs not from the
action of “oxidized” LDL, which contain hydroperoxy acyls in the phospholipids located in …
action of “oxidized” LDL, which contain hydroperoxy acyls in the phospholipids located in …