Aims The diagnosis of periprosthetic joint infection (PJI) can be difficult. All current
diagnostic tests have problems with accuracy and interpretation of results. Many new tests …

Osteomyelitis is a devastating disease caused by microbial infection of bone. While the
frequency of infection following elective orthopedic surgery is low, rates of reinfection are …

Background In addition to the significant morbidity and mortality associated with
periprosthetic joint infection (PJI), the cost of treating PJI is substantial. Prior high-quality …

Purpose Total knee arthroplasty (TKA) rates have increased substantially in the recent
decades worldwide, with Germany being one of the leading countries in the prevalence of …

Importance The human and financial costs of treating surgical site infections (SSIs) are
increasing. The number of surgical procedures performed in the United States continues to …

Staphylococcus aureus is a major human pathogen that causes a wide range of clinical
infections. It is a leading cause of bacteremia and infective endocarditis as well as …

The widespread use of biomaterials to support or replace body parts is increasingly
threatened by the risk of implant‐associated infections. In the quest for finding novel anti …

The severe infection is becoming a significant health problem which threaten the lives of
patients and the safety and economy of society. In the way of finding new strategy …

Periprosthetic joint infections are a devastating complication after arthroplasty and are
associated with substantial patient morbidity. More than 25% of revisions are attributed to …

Musculoskeletal infections (MSKI) remain the bane of orthopedic surgery, and result in
grievous illness and inordinate costs that threaten healthcare systems. As prevention …