The influence of neuroinflammation in Autism Spectrum Disorder

SM Matta, EL Hill-Yardin, PJ Crack - Brain, behavior, and immunity, 2019 - Elsevier
Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterised
by deficits in social communication and restricted or repetitive behaviours. The clinical …

Dissecting the contribution of host genetics and the microbiome in complex behaviors

SA Buffington, SW Dooling, M Sgritta, C Noecker… - Cell, 2021 - cell.com
The core symptoms of many neurological disorders have traditionally been thought to be
caused by genetic variants affecting brain development and function. However, the gut …

Probiotics and fructo-oligosaccharide intervention modulate the microbiota-gut brain axis to improve autism spectrum reducing also the hyper-serotonergic state and …

Y Wang, N Li, JJ Yang, DM Zhao, B Chen… - Pharmacological …, 2020 - Elsevier
The prevalence of autism spectrum disorders (ASD) is increasing, but its etiology remains
elusive and hence an effective treatment is not available. Previous research conducted on …

Neurodegenerative and neurodevelopmental diseases and the gut-brain axis: The potential of therapeutic targeting of the microbiome

B Bicknell, A Liebert, T Borody, G Herkes… - International journal of …, 2023 - mdpi.com
The human gut microbiome contains the largest number of bacteria in the body and has the
potential to greatly influence metabolism, not only locally but also systemically. There is an …

The gut microbiota and dysbiosis in autism spectrum disorders

HK Hughes, D Rose, P Ashwood - Current neurology and neuroscience …, 2018 - Springer
Abstract Purpose of Review There is a growing body of evidence indicating the gut
microbiota influence neurodevelopment and behavior. The purposes of this review are to …

Microbiota-brain interactions: Moving toward mechanisms in model organisms

J Nagpal, JF Cryan - Neuron, 2021 - cell.com
Changes in the microbiota are associated with alterations in nervous system structure-
function and behavior and have been implicated in the etiology of neuropsychiatric and …

The microbiota and the hypothalamus-pituitary-adrenocortical (HPA) axis, implications for anxiety and stress disorders

LM Frankiensztajn, E Elliott, O Koren - Current opinion in neurobiology, 2020 - Elsevier
Highlights•Stressful events during the perinatal period are associated with dysbiosis in the
offspring.•Stress in early life can impact the development and functioning of the …

Maternal inflammation and its ramifications on fetal neurodevelopment

HK Kwon, GB Choi, JR Huh - Trends in immunology, 2022 - cell.com
Exposure to heightened inflammation in pregnancy caused by infections or other
inflammatory insults has been associated with the onset of neurodevelopmental and …

Neuroimmune circuits in inter-organ communication

JR Huh, H Veiga-Fernandes - Nature Reviews Immunology, 2020 - nature.com
Studies in recent years have uncovered the crucial function of neuroimmune interactions in
maintaining tissue homeostasis and protection. Immune and neuronal cells are often …

[HTML][HTML] Pre/post-natal exposure to microplastic as a potential risk factor for autism spectrum disorder

J Zaheer, H Kim, IO Ko, EK Jo, EJ Choi, HJ Lee… - Environment …, 2022 - Elsevier
In common with the increase in environmental pollution in the past 10 years, there has also
been a recent increase in the prevalence of autism spectrum disorder (ASD). In this regard …