Pancreatic cancer is a highly lethal form of digestive malignancy that poses significant
health risks to individuals worldwide. Chemotherapy‐based comprehensive treatment is the …

Cancer remains a severe public health burden worldwide. One of the challenges hampering
effective cancer therapy is that the existing cancer models hardly recapitulate the tumor …

Metabolic reprogramming is known as an emerging mechanism of chemotherapy
resistance, but the metabolic signatures of pancreatic ductal adenocarcinomas (PDACs) …

Mucosal melanoma (MM), an aggressive rare subtype of melanoma, is distinct from
cutaneous melanoma and has poor prognoses. We addressed the lack of cell models for …

Luteolin (Lut) has been shown to inhibit gastric cancer (GC); however, its efficacy compared
to other clinical drugs has not been examined in human samples. This study aimed to …

Human organoids-on-chips (OrgOCs) are the synergism of human organoids (HOs)
technology and microfluidic organs-on-chips (OOCs). OOCs can mimic extrinsic …

Despite advancements in treatment protocols, cancer is one of the leading cause of deaths
worldwide. Therefore, there is a need to identify newer and personalized therapeutic targets …

Intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs)
are all considered “Pancreatic cystic neoplasms (PCNs)” and show a varying risk of …

The design of chimeric antigen receptors (CAR) significantly enhances the antitumor efficacy
of T cells. Although some CAR-T products have been approved by FDA in treating …

Organoids are three-dimensional cellular structures designed to recreate the biological
characteristics of the body's native tissues and organs in vitro. There has been a recent …