With the increasing number of patients infected with syphilis in the past 20 years, early
diagnosis and early treatment are essential to decline syphilis prevalence. Owing to its …

Syphilis is a fascinating and perplexing infection, with protean clinical manifestations and
both diagnostic and management ambiguities. Treponema pallidum subsp. pallidum, the …

The rates of syphilis are rising in the United States and many high-income nations despite
the availability of screening and effective treatment. 1–4 The diagnosis of syphilis can be …

Objective To systematically review and estimate pooled sensitivity and specificity of the
polymerase chain reaction (PCR) technique compared to recommended reference tests in …

Background Syphilis transmission is increasing, and precisely how Treponema pallidum is
transmitted sexually from person to person is unclear. We aimed to determine the frequency …

Syphilis, a re‐emerging public health problem worldwide caused by Treponema pallidum
subsp pallidum (T. pallidum), usually induces systemic and chronic inflammation in hosts …

In recent years, quantitative real-time PCR tests have been extensively developed in clinical
microbiology laboratories for routine diagnosis of infectious diseases, particularly bacterial …

Introduction Syphilis continues to be a major public health problem and the recent
resurgence in syphilis in high-income settings has seen an accompanying increase in cases …

In this report, we have developed a plasmonic ELISA strategy for the detection of syphilis.
Plasmonic ELISA is an enzyme-linked immunoassay combined with enzyme-mediated …

Objectives Macrolide resistant Treponema pallidum strains, caused by mutations in the 23S
ribosomal RNA (23S rRNA) gene, are widespread and increasingly prevalent. The authors …