Medicinal cannabis and central nervous system disorders
YT Ortiz, LR McMahon, JL Wilkerson - Frontiers in pharmacology, 2022 - frontiersin.org
Cannabinoids, including those found in cannabis, have shown promise as potential
therapeutics for numerous health issues, including pathological pain and diseases that …
therapeutics for numerous health issues, including pathological pain and diseases that …
Crosstalk between the endocannabinoid and mid-brain dopaminergic systems: Implication in dopamine dysregulation
BG Kibret, A Canseco-Alba, ES Onaivi… - Frontiers in Behavioral …, 2023 - frontiersin.org
Endocannabinoids (eCBs) and the expanded endocannabinoid system (ECS)-
“endocannabinoidome”, consists of the endogenous ligands, eCBs, their canonical and non …
“endocannabinoidome”, consists of the endogenous ligands, eCBs, their canonical and non …
Considerations for cannabinoids in perioperative care by anesthesiologists
K Laudanski, J Wain - Journal of Clinical Medicine, 2022 - mdpi.com
Increased usage of recreational and medically indicated cannabinoid compounds has been
an undeniable reality for anesthesiologists in recent years. These compounds' complicated …
an undeniable reality for anesthesiologists in recent years. These compounds' complicated …
Sleep apnea pathophysiology
G Andrisani, G Andrisani - Sleep and Breathing, 2023 - Springer
Objective The purpose of this study is to examine the pathophysiology underlying sleep
apnea (SA). Background We consider several critical features of SA including the roles …
apnea (SA). Background We consider several critical features of SA including the roles …
A preliminary investigation of the acute effects of delta-9-tetrahydrocannabinol on pain and opioid attentional bias among persons with opioid use disorder
NR Wolkowicz, M Sofuoglu, B Pittman… - Journal of Psychiatric …, 2024 - Elsevier
Introduction Attentional bias (AB) is believed to be an important factor in the development
and maintenance of both opioid use disorder (OUD) and chronic pain. Cannabis and its …
and maintenance of both opioid use disorder (OUD) and chronic pain. Cannabis and its …
Local activation of CB1 receptors by synthetic and endogenous cannabinoids dampens burst firing mode of reticular thalamic nucleus neurons in rats under ketamine …
CA Aguirre-Rodríguez, A Delgado, A Alatorre… - Experimental Brain …, 2024 - Springer
The reticular thalamic nucleus (RTN) is a thin shell that covers the dorsal thalamus and
controls the overall information flow from the thalamus to the cerebral cortex through …
controls the overall information flow from the thalamus to the cerebral cortex through …
Characterization of Gαs and Gαolf activation by catechol and non-catechol dopamine D1 receptor agonists
The dopamine D1 receptor (D1R) couples to Gαs and Gαolf and plays a crucial role in
regulating voluntary movement and other cognitive functions, making it a potential …
regulating voluntary movement and other cognitive functions, making it a potential …
Pharmaceutical Applications of Hemp
C Miyabe Shields, RD Kirk - Revolutionizing the Potential of Hemp and Its …, 2022 - Springer
Although humans have used the hemp Cannabis sativa plant for thousands of years,
recently there has been a shift in the availability of hemp products that are high in secondary …
recently there has been a shift in the availability of hemp products that are high in secondary …
Machine learning approaches to investigate the relationship between genetic factors and autism spectrum disorder
ABSTRACT Autism Spectrum Disorder (ASD) is a heterogeneous complex
neurodevelopment disorder that affects 1 to 2 percent of global population. Over the past …
neurodevelopment disorder that affects 1 to 2 percent of global population. Over the past …
ABHD6 loss-of-function in mesoaccumbens postsynaptic but not presynaptic neurons prevents diet-induced obesity
Abstract α/β-hydrolase domain 6 (ABHD6) is a lipase linked to physiological functions
affecting metabolism and body weight. Brain ABHD6 degrades 2-arachidonoylglycerol and …
affecting metabolism and body weight. Brain ABHD6 degrades 2-arachidonoylglycerol and …