Post-stroke cognitive impairment and dementia
Poststroke cognitive impairment and dementia (PSCID) is a major source of morbidity and
mortality after stroke worldwide. PSCID occurs as a consequence of ischemic stroke …
mortality after stroke worldwide. PSCID occurs as a consequence of ischemic stroke …
Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation
JAHR Claassen, DHJ Thijssen… - Physiological …, 2021 - journals.physiology.org
Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …
[HTML][HTML] A human brain vascular atlas reveals diverse mediators of Alzheimer's risk
The human brain vasculature is of great medical importance: its dysfunction causes
disability and death, and the specialized structure it forms—the blood–brain barrier …
disability and death, and the specialized structure it forms—the blood–brain barrier …
Cognitive impairment after ischemic and hemorrhagic stroke: a scientific statement from the American Heart Association/American Stroke Association
Purpose: Cognitive impairment is a common consequence of stroke and has direct
implications for poststroke functioning and quality of life, including the ability to maintain a …
implications for poststroke functioning and quality of life, including the ability to maintain a …
[HTML][HTML] Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
COVID‐19 and dementia: Analyses of risk, disparity, and outcomes from electronic health records in the US
QQ Wang, PB Davis, ME Gurney… - Alzheimer's & Dementia, 2021 - Wiley Online Library
Introduction At present, there is limited data on the risks, disparity, and outcomes for COVID‐
19 in patients with dementia in the United States. Methods This is a retrospective case …
19 in patients with dementia in the United States. Methods This is a retrospective case …
[HTML][HTML] Defining blood-induced microglia functions in neurodegeneration through multiomic profiling
Blood protein extravasation through a disrupted blood–brain barrier and innate immune
activation are hallmarks of neurological diseases and emerging therapeutic targets …
activation are hallmarks of neurological diseases and emerging therapeutic targets …
[HTML][HTML] Blood-brain barrier: from physiology to disease and back
MD Sweeney, Z Zhao, A Montagne… - Physiological …, 2018 - journals.physiology.org
The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …
pathogens from entering the brain. At the same time, the BBB regulates transport of …
[HTML][HTML] Blood–brain barrier breakdown: an emerging biomarker of cognitive impairment in normal aging and dementia
B Hussain, C Fang, J Chang - Frontiers in neuroscience, 2021 - frontiersin.org
The blood–brain barrier (BBB) plays a vital role in maintaining the specialized
microenvironment of the neural tissue. It separates the peripheral circulatory system from the …
microenvironment of the neural tissue. It separates the peripheral circulatory system from the …
[HTML][HTML] Vascular cognitive impairment (VCI)
Vascular cognitive impairment (VCI) is predominately caused by vascular risk factors and
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …