Cartilage-related collagens in osteoarthritis and rheumatoid arthritis: from pathogenesis to therapeutics

Z Ouyang, L Dong, F Yao, K Wang, Y Chen… - International Journal of …, 2023 - mdpi.com
Collagens serve essential mechanical functions throughout the body, particularly in the
connective tissues. In articular cartilage, collagens provide most of the biomechanical …

Elderly-onset rheumatoid arthritis: characteristics and treatment options

S Pavlov-Dolijanovic, M Bogojevic, T Nozica-Radulovic… - Medicina, 2023 - mdpi.com
Elderly-onset rheumatoid arthritis (EORA) is a distinct clinical entity defined as the onset of
rheumatoid arthritis (RA) in individuals aged over 60 years. EORA presents unique clinical …

Novel potential janus kinase inhibitors with therapeutic prospects in rheumatoid arthritis addressed by in silico studies

AF Radu, SG Bungau, AP Negru, B Uivaraseanu… - Molecules, 2023 - mdpi.com
Rheumatoid arthritis (RA) is a debilitating autoimmune disorder with an inflammatory
condition targeting the joints that affects millions of patients worldwide. Several unmet needs …

Enhancement efficiency delivery of antiviral Molnupiravir-drug via the loading with self-assembly nanoparticles of pycnogenol and cellulose which are decorated by …

NM El-Shafai, YS Mostafa, MS Ramadan… - Bioorganic …, 2024 - Elsevier
The target of the study is to modify the efficiency of Molnupiravir-drug (MOL) for COVID-19
therapy via the rearrangement of the building engineering of MOL-drug by loading it with self …

Potential roles of air pollutants on the induction and aggravation of rheumatoid arthritis: From cell to bedside studies

W Gumtorntip, N Kasitanon, W Louthrenoo… - Environmental …, 2023 - Elsevier
Rheumatoid arthritis (RA) is an involving chronic systemic inflammatory disease which
mainly affects the joints. Several factors including genetic, environment and infections have …

[HTML][HTML] Suppressive effect of Tripterygium hypoglaucum (Levl.) Hutch extract on rheumatoid arthritis in mice by modulating inflammasome and bile acid metabolism

J Zheng, J Hu, Y Yang, L Xiong, H Yang… - Biomedicine & …, 2023 - Elsevier
Abstract Tripterygium hypoglaucum (Levl.) Hutch (THH) has long been used as a remedy for
rheumatoid arthritis (RA) in China. However, it is unclear whether the anti-RA mechanism of …

The integral role of diets including natural products to manage rheumatoid arthritis: a narrative review

A Gunes-Bayir, B Mendes, A Dadak - Current Issues in Molecular Biology, 2023 - mdpi.com
Genetic and environmental factors including lifestyle are thought to play a key role in the
pathophysiology of rheumatoid arthritis (RA). There is evidence that diet can enhance the …

Exploring the Therapeutic Potential of Ammodaucus leucotrichus Seed Extracts: A Multi-Faceted Analysis of Phytochemical Composition, Anti-Inflammatory Efficacy …

C Djehiche, N Benzidane, H Djeghim, M Tebboub… - Pharmaceuticals, 2024 - mdpi.com
Ammodaucus leucotrichus exhibits promising pharmacological activity, hinting at anti-
inflammatory and anti-arthritic effects. This study investigated seed extracts from …

Long-Term Retention Rate of Tofacitinib in Rheumatoid Arthritis: An Italian Multicenter Retrospective Cohort Study

M Paroli, A Becciolini, E Bravi, R Andracco, V Nucera… - Medicina, 2023 - mdpi.com
Background: Tofacitinib (TOFA) was the first Janus kinase inhibitor (JAKi) to be approved for
the treatment of rheumatoid arthritis (RA). However, data on the retention rate of TOFA …

Current trends in epigenetic, cellular and molecular pathways in management of rheumatoid arthritis

R Makkar, A Sehgal, S Singh, N Sharma, R Rawat… - …, 2023 - Springer
Rheumatoid arthritis is a systemic chronic polyarticular autoimmune disorder of joints and
joint membrane mainly affecting feet and hands. The pathological manifestation of the …