[HTML][HTML] Opportunities and challenges of CD47-targeted therapy in cancer immunotherapy

Q Chen, X Guo, W Ma - Oncology Research, 2024 - ncbi.nlm.nih.gov
Cancer immunotherapy has emerged as a promising strategy for the treatment of cancer,
with the tumor microenvironment (TME) playing a pivotal role in modulating the immune …

Thrombospondin-1 in drug activity and tumor response to therapies

E Longhi, L Carminati, E Carlessi, D Belotti… - Seminars in Cell & …, 2024 - Elsevier
Thrombospondins (TSPs) have numerous different roles in cancer, regulating the behavior
of cancer cells and non-neoplastic cells, and defining the responses of tumor cells to …

Unveiling the Potential of Extracellular Vesicles as Biomarkers and Therapeutic Nanotools for Gastrointestinal Diseases

V Arrè, R Mastrogiacomo, F Balestra, G Serino, F Viti… - Pharmaceutics, 2024 - mdpi.com
Extracellular vesicles (EVs), acting as inherent nanocarriers adept at transporting a range of
different biological molecules such as proteins, lipids, and genetic material, exhibit diverse …

[HTML][HTML] Invadopodia associated Thrombospondin-1 contributes to a post-therapy pro-invasive response in glioblastoma cells

CA Whitehead, AP Morokoff, AH Kaye… - Experimental Cell …, 2023 - Elsevier
A critical challenge in the treatment of glioblastoma (GBM) is its highly invasive nature which
promotes cell migration throughout the brain and hinders surgical resection and effective …

[HTML][HTML] Integrating bulk RNA-seq and scRNA-seq analyses revealed the function and clinical value of thrombospondins in colon cancer

J Li, Y Tang, F Long, L Tian, A Tang, LH Ding… - Computational and …, 2024 - Elsevier
Background Acting as mediators in cell-matrix and cell-cell communication, matricellular
proteins play a crucial role in cancer progression. Thrombospondins (TSPs), a type of …

[引用][C] Thrombospondin proteins–Versatile extracellular proteins with multiple biological functions

KW Adolph - Seminars in Cell and Developmental Biology, 2024 - experts.umn.edu
Thrombospondin proteins – Versatile extracellular proteins with multiple biological functions
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