PGRMC1: An enigmatic heme-binding protein
MR McGuire, PJ Espenshade - Pharmacology & therapeutics, 2023 - Elsevier
Abstract Progesterone Receptor Membrane Component 1 (PGRMC1) is a heme-binding
protein that has been implicated in a wide range of cell and tissue functions, including …
protein that has been implicated in a wide range of cell and tissue functions, including …
Pleiotropic actions of PGRMC proteins in cancer
JK Pru - Endocrinology, 2022 - academic.oup.com
Progesterone receptor membrane component (PGRMC) proteins play important roles in
tumor growth, progression, and chemoresistance, of which PGRMC1 is the best …
tumor growth, progression, and chemoresistance, of which PGRMC1 is the best …
Hepatic progesterone receptor membrane component 1 attenuates ethanol-induced liver injury by reducing acetaldehyde production and oxidative stress
SL Jo, IJ Baek, JW Ko, HJ Kwun… - American Journal of …, 2023 - journals.physiology.org
Alcohol-associated liver disease (ALD) is caused by excessive abuse of alcohol. One of the
most representative causes of ALD is the action of acetaldehyde. Acetaldehyde is a toxic …
most representative causes of ALD is the action of acetaldehyde. Acetaldehyde is a toxic …
Molecular programming modulates hepatic lipid metabolism and adult metabolic risk in the offspring of obese mothers in a sex-specific manner
C Savva, LA Helguero, M González-Granillo… - Communications …, 2022 - nature.com
Male and female offspring of obese mothers are known to differ extensively in their
metabolic adaptation and later development of complications. We investigate the sex …
metabolic adaptation and later development of complications. We investigate the sex …
Quo vadis PGRMC? Grand-scale biology in human health and disease
MA Cahill - Frontiers in Bioscience-Landmark, 2022 - researchoutput.csu.edu.au
The title usage of Latin Quo vadis 'where are you going'extends the question Unde venisti
from where 'did you come?'posed in the accompanying paper and extends consideration of …
from where 'did you come?'posed in the accompanying paper and extends consideration of …
[PDF][PDF] Unde venisti PGRMC? Grand-scale biology from early eukaryotes and eumetazoan animal origins
MA Cahill - Frontiers in Bioscience-Landmark, 2022 - researchoutput.csu.edu.au
The title usage of Unde venisti 'from where have you come'is from a now dead language
(Latin) that foundationally influenced modern English (not the major influence, but an …
(Latin) that foundationally influenced modern English (not the major influence, but an …
[HTML][HTML] Impact of somatic mutations on clinical and pathologic outcomes in borderline resectable and locally advanced pancreatic cancer treated with neoadjuvant …
Purpose The purpose of this study was to determine if somatic mutations are associated with
clinical and pathologic outcomes in patients with borderline resectable pancreatic cancer …
clinical and pathologic outcomes in patients with borderline resectable pancreatic cancer …
Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression, the Immune Microenvironment and the Response to Therapy in …
CA Dumitru, H Schröder, FTA Schäfer, JF Aust… - Cells, 2023 - mdpi.com
Progesterone Receptor Membrane Component 1 (PGRMC1) is a tumour-promoting factor in
several types of cancer but its role in brain tumours is poorly characterized thus far. Our …
several types of cancer but its role in brain tumours is poorly characterized thus far. Our …
Progesterone Receptor Membrane Component 1 Regulates Cellular Stress Responses and Inflammatory Pathways in Chronic Neuroinflammatory Conditions
SL Jo, EJ Hong - Antioxidants, 2024 - mdpi.com
Alzheimer's disease (AD) is the leading cause of dementia and is one of the
neurodegenerative diseases that are caused by neuronal death due to various triggers …
neurodegenerative diseases that are caused by neuronal death due to various triggers …
Pleiotropy of Progesterone Receptor Membrane Component 1 in Modulation of Cytochrome P450 Activity
IS Barata, J Rueff, M Kranendonk, F Esteves - Journal of Xenobiotics, 2024 - mdpi.com
Progesterone receptor membrane component 1 (PGRMC1) is one of few proteins that have
been recently described as direct modulators of the activity of human cytochrome P450 …
been recently described as direct modulators of the activity of human cytochrome P450 …