Infections caused by acute respiratory viruses induce a systemic innate immune response,
which can be measured by the increased levels of expression of inflammatory genes in …

Thyroid hormones are involved in many biological processes such as neurogenesis,
metabolism, and development. However, compounds called endocrine disruptors can alter …

Introduction Spontaneous control of HIV-1 replication in the absence of anti-retroviral
therapy (ART) naturally occurs in a small proportion of HIV-1-infected individuals known as …

Recent studies have implicated the phenazine biosynthesis-like domain-containing protein
(PBLD) in the negative regulation of the development and progression of various cancers …

Abstract Background Interferon Regulatory Factor 3 (IRF3) is a transcription factor that plays
a crucial role in the innate immune response by recognizing and responding to foreign …

Osteoarthritis (OA) is a chronic degenerative joint disease characterized by cartilage
degeneration and subchondral bone remodelling. Currently, conservative treatment …

While certain members of ubiquitin-coupled enzymes (E2s) have garnered attention as
potential therapeutic targets across diverse diseases, research progress on Ubiquitin …

Porcine respiratory and reproductive syndrome (PRRS) is one of the most devastating
infectious diseases of pigs, causing reproductive failures in sows and severe respiratory …

Inflammatory response in macrophages on account of prostheses-derived wear particles is
the leading cause of artificial joint failure. However, the mechanism by which wear particles …

The study of human neurological infection faces many technical and ethical challenges.
While not as common as mammalian models, the use of Drosophila (fruit fly) in the …