RNF5 is an E3 ubiquitin ligase involved in various physiological processes such as protein
localization and cancer progression. Recent studies have shown that RNF5 significantly …

Background TANK-binding kinase 1 (TBK1) is a pivotal mediator of innate immunity,
activated by receptors such as mitochondrial antiviral signaling protein (MAVS), stimulator of …

The interferon regulatory factors (IRFs) family comprises 11 members that are involved in
various biological processes such as antiviral defense, cell proliferation regulation …

Molluscum contagiosum virus (MCV) is a human-specific poxvirus that causes a highly
common but mild infection characterized by distinctive and persistent papular skin lesions …

Interferons were the original prototype cytokine system discovered in 20th-century research.
As the name implies, they were originally thought to be synthesised and secreted between …

Viral hemorrhagic septicemia virus (VHSV) poses a significant threat to the aquaculture
industry, prompting the need for effective preventive measures. Here, we developed an …

Inhibitors of NF-κB (IκBs) have been implicated as major components of the Rel/NF-κB
signaling pathway, playing an important negative regulatory role in host antiviral immunity …

Background Polycystic ovary syndrome (PCOS) is the most common reproductive-endocrine
condition in premenopausal women. Troxerutin, a common clinical anti-coagulant agent …

Background Promyelocytic leukemia protein (PML) is a primary component of PML nuclear
bodies (PML-NBs). PML and PML-NBs play critical roles in processes like the cell cycle …

Ebola virus (EBOV) is a zoonotic virus comprising of six known different species, designated
within the family Filoviridae and genus Ebolavirus. The first recorded outbreak of an EBOV …