The intestinal mucosa provides a selective permeable barrier for nutrient absorption and
protection from external factors. It consists of epithelial cells, immune cells and their …

Dynamic interactions between gut microbiota and a host's innate and adaptive immune
systems are essential in maintaining intestinal homeostasis and inhibiting inflammation. Gut …

The most prevalent diseases of our time, non-communicable diseases (NCDs)(including
obesity, type 2 diabetes, cardiovascular diseases and some types of cancer) are rising …

Inflammatory bowel disease (IBD) is a chronic and life‐threating inflammatory disease of
gastroenteric tissue characterized by episodes of intestinal inflammation. The pathogenesis …

Inflammatory bowel disease (IBD) is a chronic immune-mediated disease affecting the
gastrointestinal tract. IBD consists of 2 subtypes: ulcerative colitis and Crohn disease. IBD is …

The gut microbiota is a complex community of microorganisms that inhabit the digestive
tracts of humans, living in symbiosis with the host. Dysbiosis, characterized by an imbalance …

Changes in the composition of gut-associated microbial communities are associated with
many human illnesses, but the factors driving dysbiosis remain incompletely understood …

Inflammatory bowel diseases (IBDs), represented by Crohn disease and ulcerative colitis,
are associated with major morbidity in Western countries and with increasing incidence in …

Constant remodeling of tight junctions to regulate trans-epithelial permeability is essential in
maintaining intestinal barrier functions and thus preventing diffusion of small molecules and …

A key challenge for the effective treatment of gastrointestinal diseases including
inflammatory bowel disease is to develop an orally administered drug delivery system …