Animal studies demonstrate that noise exposure can permanently damage the synapses
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …

Abstract Models of the human auditory periphery range from very basic functional
descriptions of auditory filtering to detailed computational models of cochlear mechanics …

Cochlear synaptopathy is the noise-induced or age-related loss of ribbon synapses between
inner hair cells (IHCs) and auditory-nerve fibers (ANFs), first reported in CBA/CaJ mice …

Understanding the biology of the previously underappreciated sensitivity of cochlear
synapses to noise insult, and its clinical consequences, is becoming a mission for a growing …

An estimate of lifetime noise exposure was used as the primary predictor of performance on
a range of behavioral tasks: frequency and intensity difference limens, amplitude modulation …

Studies in multiple species, including in post-mortem human tissue, have shown that normal
aging and/or acoustic overexposure can lead to a significant loss of afferent synapses …

In social settings, speech waveforms from nearby speakers mix together in our ear canals.
Normally, the brain unmixes the attended speech stream from the chorus of background …

Several studies identified hearing loss as a risk factor for aging-related processes, including
neurodegenerative diseases, as dementia and age-related hearing loss (ARHL). Although …

Several studies identified noise-induced hearing loss (NIHL) as a risk factor for sensory
aging and cognitive decline processes, including neurodegenerative diseases, such as …

Objective: Short-term noise exposure that induces transient changes in thresholds has
induced permanent cochlear synaptopathy in multiple species. Here, the literature was …