Deciphering compromised speech-in-noise intelligibility in older listeners: the influence of cochlear synaptopathy

M Garrett, V Vasilkov, M Mauermann, JL Wilson… - bioRxiv, 2020 - biorxiv.org
Damage to auditory-nerve-fiber synapses (ie cochlear synaptopathy) degrades the neural
coding of sound and is predicted to impair sound perception in noisy listening environments …

[PDF][PDF] Cochlear Synaptopathy Following Noise Exposure in Guinea Pigs: Its Electrophysiological and Histological Assessments.

P Mahdi, A Pourbakht, VP Mahabadi… - Sound & …, 2020 - cdn.techscience.cn
Exposure to high level of noise, may cause the permanent cochlear synaptic degeneration.
In present study, a model of noise induced cochlear synaptopathy was established and the …

Noise-Induced Hearing Loss and Drug Therapy: Basic and Translational Science

C Escabi, M Trevino, E Bielefeld… - New Therapies to Prevent …, 2020 - Springer
Noise-induced hearing loss is the second leading cause of hearing impairment. The
purpose of this chapter is to familiarize the reader with the anatomical, physiological, and …

Loss of function mutation of the receptor guanylyl cyclase B (GC-B) leads to changes in features of auditory processing

S Wolter - 2019 - tobias-lib.ub.uni-tuebingen.de
The guanylyl cyclase B (GC-B) was recently shown to be important for proper wiring of
sensory axons of dorsal root ganglions (DRGs) as well as cranial sensory ganglions (CSGs) …

Investigating the Relationship between Subcortical and Cortical Auditory Processing

S Varma - 2019 - search.proquest.com
The auditory system is highly integrative, with feedforward and feedback connections from
periphery to cortex (and stages in between). In order to understand how the different levels …

Effects of Aging and Corticofugal Modulation on Startle Behavior and Auditory Physiology

M Dowling - 2019 - search.proquest.com
Frequency-modulated (FM) sweeps play a key role in species specific communication.
Evidence from previous studies have shown that central auditory processing has been …

Search for Electrophysiological Indices of Hidden Hearing Loss

CH Suresh - 2018 - search.proquest.com
Recent studies in animals indicate that even moderate levels of exposure to noise can
damage synaptic ribbons between the inner hair cells and auditory nerve fibers without …

Noise Exposure, Self-Reported Speech-in-Noise Percpetion, and the Auditory Brainstem Response in Normal-Hearing Human Ears

N Go - 2018 - kuscholarworks.ku.edu
Difficulty understanding speech-in-noise (SIN) is a common complaint among many
listeners. There is emerging evidence that noise exposure is associated with difficulties in …

Dynamic gain adjustments in descending corticofugal outputs from auditory cortex compensate for cochlear nerve synaptic damage

MM Asokan, RS Williamson, KE Hancock, DB Polley - bioRxiv, 2017 - biorxiv.org
Abstract Layer 5 (L5) cortical projection neurons innervate far-ranging brain areas to
coordinate integrative sensory processing and adaptive behaviors. Here, we characterize a …

[引用][C] Degradation of auditory processing and perception with age: The role of near and supra-threshold sensorineural hearing deficits

M Garrett - 2020 - biblio.ugent.be
Ageing and noise exposure are the most common factors linked to the development of
sensorineural hearing loss (SNHL), which reduces the ability to perceive and make sense of …