Linking anatomical and physiological markers of auditory system degeneration with behavioral hearing assessments in a mouse (Mus musculus) model of age-related …
A Kobrina, KM Schrode, LA Screven, H Javaid… - Neurobiology of …, 2020 - Elsevier
Age-related hearing loss is a very common sensory disability, affecting one in three older
adults. Establishing a link between anatomical, physiological, and behavioral markers of …
adults. Establishing a link between anatomical, physiological, and behavioral markers of …
Redox imbalance as a common pathogenic factor linking hearing loss and cognitive decline
F Paciello, C Ripoli, AR Fetoni, C Grassi - Antioxidants, 2023 - mdpi.com
Experimental and clinical data suggest a tight link between hearing and cognitive functions
under both physiological and pathological conditions. Indeed, hearing perception requires …
under both physiological and pathological conditions. Indeed, hearing perception requires …
Age-related changes in neural coding of envelope cues: peripheral declines and central compensation
A Parthasarathy, EL Bartlett, SG Kujawa - Neuroscience, 2019 - Elsevier
Aging listeners often experience difficulties in perceiving temporally complex acoustic cues
in noisy environments. These difficulties likely have neurophysiological contributors from …
in noisy environments. These difficulties likely have neurophysiological contributors from …
Investigating the effect of cochlear synaptopathy on envelope following responses using a model of the auditory nerve
The healthy auditory system enables communication in challenging situations with high
levels of background noise. Yet, despite normal sensitivity to pure tones, many listeners …
levels of background noise. Yet, despite normal sensitivity to pure tones, many listeners …
Enhanced central neural gain compensates acoustic trauma-induced cochlear impairment, but unlikely correlates with tinnitus and hyperacusis
D Möhrle, B Hofmeier, M Amend, S Wolpert, K Ni… - Neuroscience, 2019 - Elsevier
For successful future therapeutic strategies for tinnitus and hyperacusis, a subcategorization
of both conditions on the basis of differentiated neural correlates would be of invaluable …
of both conditions on the basis of differentiated neural correlates would be of invaluable …
Increased central auditory gain in 5xFAD Alzheimer's disease mice as an early biomarker candidate for Alzheimer's disease diagnosis
Alzheimer's Disease (AD) is a neurodegenerative illness without a cure. All current therapies
require an accurate diagnosis and staging of AD to ensure appropriate care. Central …
require an accurate diagnosis and staging of AD to ensure appropriate care. Central …
[HTML][HTML] Disturbed balance of inhibitory signaling links hearing loss and cognition
Neuronal hyperexcitability in the central auditory pathway linked to reduced inhibitory
activity is associated with numerous forms of hearing loss, including noise damage, age …
activity is associated with numerous forms of hearing loss, including noise damage, age …
Central compensation in auditory brainstem after damaging noise exposure
Noise exposure is one of the most common causes of hearing loss and peripheral damage
to the auditory system. A growing literature suggests that the auditory system can …
to the auditory system. A growing literature suggests that the auditory system can …
Neural signatures of temporal regularity processing in sounds differ between younger and older adults
B Herrmann, C Buckland, IS Johnsrude - Neurobiology of Aging, 2019 - Elsevier
Sensitivity to temporal regularity (eg, recurring modulation in amplitude) is crucial for speech
perception. Degradation of the auditory periphery due to aging and hearing loss may lead to …
perception. Degradation of the auditory periphery due to aging and hearing loss may lead to …
Aging alters envelope representations of speech-like sounds in the inferior colliculus
Hearing impairment in older people is thought to arise from impaired temporal processing in
auditory circuits. We used a systems-level (scalp recordings) and a microcircuit-level …
auditory circuits. We used a systems-level (scalp recordings) and a microcircuit-level …