Current topics in hearing research: Deafferentation and threshold independent hearing loss

M Trevino, E Lobarinas - Hearing research, 2022 - Elsevier
Hearing research findings in recent years have begun to change how we think about
hearing loss and how we consider the risk of auditory damage from noise exposure. These …

Ontogeny of auditory brainstem responses in the bat, Phyllostomus discolor

M Linnenschmidt, L Wiegrebe - Hearing Research, 2019 - Elsevier
Hearing is the primary sensory modality in bats, but its development is poorly studied. For
newborns, hearing appears essential in maintaining contact with their mothers and to …

Applicability of subcortical EEG metrics of synaptopathy to older listeners with impaired audiograms

M Garrett, S Verhulst - Hearing research, 2019 - Elsevier
Emerging evidence suggests that cochlear synaptopathy is a common feature of
sensorineural hearing loss, but it is not known to what extent electrophysiological metrics …

[PDF][PDF] Baatenburg de Jong, RJ, Ikram, MA, Nagtegaal, AP, & Goedegebure, A.(2020). Assessing hearing loss in older adults with a single question and person …

BC Oosterloo, NC Homans - PLoS One, 2020 - pure.eur.nl
Hearing loss (HL) is a frequent problem among the elderly and has been studied in many
cohort studies. However, pure tone audiometry—the gold standard—is rather time …

[PDF][PDF] Age-related central gain compensation for reduced auditory nerve output for people with normal audiograms, with and without tinnitus

PT Johannesen, EA Lopez-Poveda - Iscience, 2021 - cell.com
Central gain compensation for reduced auditory nerve output has been hypothesized as a
mechanism for tinnitus with a normal audiogram. Here, we investigate if gain compensation …

Age-related changes in envelope-following responses at equalized peripheral or central activation

J Lai, AL Sommer, EL Bartlett - Neurobiology of aging, 2017 - Elsevier
Previous work has debated about the comparisons of hearing abilities faced with alterations
in hearing thresholds and evoked potentials between groups following acoustic trauma-or …

[HTML][HTML] Effects of age on electrophysiological measures of cochlear synaptopathy in humans

S Carcagno, CJ Plack - Hearing Research, 2020 - Elsevier
Age-related cochlear synaptopathy (CS) has been shown to occur in rodents with minimal
noise exposure, and has been hypothesized to play a crucial role in age-related hearing …

NO-sensitive guanylate cyclase isoforms NO-GC1 and NO-GC2 contribute to noise-induced inner hair cell synaptopathy

D Möhrle, K Reimann, S Wolter, M Wolters… - Molecular …, 2017 - ASPET
Nitric oxide (NO) activates the NO-sensitive soluble guanylate cyclase (NO-GC, sGC) and
triggers intracellular signaling pathways involving cGMP. For survival of cochlear hair cells …

[HTML][HTML] Oxidative Stress Plays an Important Role in Glutamatergic Excitotoxicity-Induced Cochlear Synaptopathy: Implication for Therapeutic Molecules Screening

AR Saidia, F François, F Casas, I Mechaly, S Venteo… - Antioxidants, 2024 - mdpi.com
The disruption of the synaptic connection between the sensory inner hair cells (IHCs) and
the auditory nerve fiber terminals of the type I spiral ganglion neurons (SGN) has been …

Music as a unique source of noise-induced hearing loss

A Reynolds, EC Bielefeld - Hearing Research, 2023 - Elsevier
Music is among the most important artistic, cultural, and entertainment modalities in any
society. With the proliferation of music genres and the technological advances that allow …