[HTML][HTML] Cancer stem cells in renal cell carcinoma: origins and biomarkers

F Lasorsa, M Rutigliano, M Milella, M Ferro… - International Journal of …, 2023 - mdpi.com
The term “cancer stem cell”(CSC) refers to a cancer cell with the following features:
clonogenic ability, the expression of stem cell markers, differentiation into cells of different …

[HTML][HTML] Molecular mechanisms of kidney injury and repair

S Rayego-Mateos, L Marquez-Expósito… - International Journal of …, 2022 - mdpi.com
Chronic kidney disease (CKD) will become the fifth global cause of death by 2040, thus
emphasizing the need to better understand the molecular mechanisms of damage and …

β‐catenin‐controlled tubular cell‐derived exosomes play a key role in fibroblast activation via the OPN‐CD44 axis

S Chen, M Zhang, J Li, J Huang, S Zhou… - Journal of …, 2022 - Wiley Online Library
Tubular injury and peripheral fibroblast activation are the hallmarks of chronic kidney
disease (CKD), suggesting intimate communication between the two types of cells …

In-vitro and in-vivo biocompatibility of dECM-alginate as a promising candidate in cell delivery for kidney regeneration

TL Chu, G Tripathi, M Park, SH Bae, BT Lee - International Journal of …, 2022 - Elsevier
In this study, kidney decellularized extracellular matrix (dECM) and alginate (ALG) hybrid
injectable hydrogel, with the purpose of delivering progenitor cells for tissue engineering …

[HTML][HTML] Cellular milieu in clear cell renal cell carcinoma

AM Raghubar, MJ Roberts, S Wood, HG Healy… - Frontiers in …, 2022 - frontiersin.org
Clear cell renal cell carcinoma (ccRCC) is globally the most prevalent urological cancer. The
cells of origin in ccRCC have been identified as proximal tubular epithelial cells (PTEC) …

[HTML][HTML] The effect of chemotherapy and radiotherapy on stem cells and wound healing. Current perspectives and challenges for cell-based therapies

M Zawrzykraj, M Deptuła, K Kondej, A Tymińska… - Biomedicine & …, 2023 - Elsevier
Cancers are part of the group of diseases that carry a high mortality rate. According to World
Health Organization in 2020 reported 10 million deaths due to cancers. Treatment of …

[HTML][HTML] Natural products for kidney disease treatment: Focus on targeting mitochondrial dysfunction

J Huang, Y Liang, L Zhou - Frontiers in Pharmacology, 2023 - frontiersin.org
Kidney is a key organ in human body to excrete toxins and sustain the balance of water and
electrolyte. In its embryonic development and disease evolution, kidney endures enormous …

[HTML][HTML] Innovative nanotechnology tools for the functional control and tracking of human stem cells

A Marino, M Battaglini, C Tapeinos, A Larranaga… - Materials today …, 2022 - Elsevier
The precise control of stem cell behavior, including differentiation, transdifferentiation, and
reprogramming, is fundamental for safely and efficiently using human stem cells in …

[HTML][HTML] Meta-analysis of single-cell and single-nucleus transcriptomics reveals kidney cell type consensus signatures

M Quatredeniers, AS Serafin, A Benmerah, A Rausell… - Scientific Data, 2023 - nature.com
While the amount of studies involving single-cell or single-nucleus RNA-sequencing
technologies grows exponentially within the biomedical research area, the kidney field …

Bone marrow-derived mesenchymal stem cells transplantation attenuates renal fibrosis following acute kidney injury in rats by diminishing pericyte-myofibroblast …

H Wang, M Li, L Fei, C Xie, L Ding, C Zhu… - Transplantation …, 2023 - Elsevier
Background Renal fibrosis is a common chronic outcome of acute kidney injury (AKI).
Pericyte-myofibroblasts transition and production of abundant extracellular matrix are the …