Bronchial asthma (BA) is a chronic inflammatory disease with a marked heterogeneity in
pathophysiology and etiology. The heterogeneity of BA may be related to the inducing …

Abstract Purpose of Review Increases in ambient levels of air pollutants have been linked to
lung inflammation and remodeling, processes that lead to the development and …

Introduction: When rhinosinusitis–the inflammation of the nasal cavity and paranasal
sinuses–persists for over 12 weeks, it is termed 'chronic rhinosinusitis'(CRS). Both innate …

The airway epithelium provides the first line of defense to the surrounding environment.
However, dysfunctions of this physical barrier are frequently observed in allergic diseases …

Allergic asthma is a chronic inflammatory disease of the airways that is driven by
maladaptive T helper 2 (Th2) and Th17 immune responses against harmless, airborne …

The Th (T helper) 2 response is characteristic of allergic asthma, and Th17 cells are involved
in more severe asthma. Recent studies demonstrated that HMGB1 (High mobility group box …

The lungs are vulnerable to attack by respiratory insults such as toxins, allergens, and
pathogens, given their continuous exposure to the air we breathe. Our immune system has …

Dendritic cells (DC s) are professional antigen‐presenting cells that play a key role in
directing T‐cell responses. Regulatory T (Treg) cells possess an immunosuppressive ability …

Abstract The CD4+ CD25+ Foxp3+ regulatory T cells (Tregs) are known to regulate Th2-
induced allergic rhinitis (AR). In this study, we evaluated the efficacy of Derp1-modified …

This study aimed to investigate whether bone marrow‐derived mesenchymal stem cells (BM‐
MSCs) can inhibit function of dendritic cells (DCs) by secreting Galectin‐1 (Gal‐1). BM …