Interactions between bacterial and phage communities in natural environments
We commonly acknowledge that bacterial viruses (phages) shape the composition and
evolution of bacterial communities in nature and therefore have important roles in ecosystem …
evolution of bacterial communities in nature and therefore have important roles in ecosystem …
Horizontal gene transfer of antibiotic resistance genes in biofilms
C Michaelis, E Grohmann - Antibiotics, 2023 - mdpi.com
Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix
which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it …
which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it …
[HTML][HTML] Programmable protein delivery with a bacterial contractile injection system
Endosymbiotic bacteria have evolved intricate delivery systems that enable these organisms
to interface with host biology. One example, the extracellular contractile injection systems …
to interface with host biology. One example, the extracellular contractile injection systems …
Mechanisms and clinical importance of bacteriophage resistance
JE Egido, AR Costa… - FEMS microbiology …, 2022 - academic.oup.com
We are in the midst of a golden age of uncovering defense systems against bacteriophages.
Apart from the fundamental interest in these defense systems, and revolutionary applications …
Apart from the fundamental interest in these defense systems, and revolutionary applications …
The pan-immune system of bacteria: antiviral defence as a community resource
A Bernheim, R Sorek - Nature reviews microbiology, 2020 - nature.com
Viruses and their hosts are engaged in a constant arms race leading to the evolution of
antiviral defence mechanisms. Recent studies have revealed that the immune arsenal of …
antiviral defence mechanisms. Recent studies have revealed that the immune arsenal of …
Marine DNA viral macro-and microdiversity from pole to pole
Microbes drive most ecosystems and are modulated by viruses that impact their lifespan,
gene flow, and metabolic outputs. However, ecosystem-level impacts of viral community …
gene flow, and metabolic outputs. However, ecosystem-level impacts of viral community …
Global trends in marine plankton diversity across kingdoms of life
The ocean is home to myriad small planktonic organisms that underpin the functioning of
marine ecosystems. However, their spatial patterns of diversity and the underlying drivers …
marine ecosystems. However, their spatial patterns of diversity and the underlying drivers …
Phage cocktail development for bacteriophage therapy: toward improving spectrum of activity breadth and depth
Phage therapy is the use of bacterial viruses as antibacterial agents. A primary
consideration for commercial development of phages for phage therapy is the number of …
consideration for commercial development of phages for phage therapy is the number of …
Bacteriophage therapy: clinical trials and regulatory hurdles
LL Furfaro, MS Payne, BJ Chang - Frontiers in cellular and infection …, 2018 - frontiersin.org
Increasing reports of antimicrobial resistance and limited new antibiotic discoveries and
development have fuelled innovation in other research fields and led to a revitalization of …
development have fuelled innovation in other research fields and led to a revitalization of …
RNA-targeting CRISPR–Cas systems
SPB van Beljouw, J Sanders… - Nature Reviews …, 2023 - nature.com
CRISPR–Cas is a widespread adaptive immune system in bacteria and archaea that
protects against viral infection by targeting specific invading nucleic acid sequences …
protects against viral infection by targeting specific invading nucleic acid sequences …