Viral communities contribute more to the lysis of antibiotic-resistant bacteria than the transduction of antibiotic resistance genes in anaerobic digestion revealed by …

J Zhang, T Lu, Y Song, UN Rocha, J Liu… - Environmental …, 2024 - ACS Publications
Ecological role of the viral community on the fate of antibiotic resistance genes
(ARGs)(reduction vs proliferation) remains unclear in anaerobic digestion (AD) …

Going viral: emerging opportunities for phage-based bacterial control in water treatment and reuse

J Mathieu, P Yu, P Zuo, MLB Da Silva… - Accounts of chemical …, 2019 - ACS Publications
Conspectus Water security to protect human lives and support sustainable development is
one of the greatest global challenges of this century. While a myriad of water pollutants can …

Virulent coliphages in 1-year-old children fecal samples are fewer, but more infectious than temperate coliphages

A Mathieu, M Dion, L Deng, D Tremblay… - Nature …, 2020 - nature.com
Bacteriophages constitute an important part of the human gut microbiota, but their impact on
this community is largely unknown. Here, we cultivate temperate phages produced by 900 E …

Validation of the application of gel beads-based single-cell genome sequencing platform to soil and seawater

Y Nishikawa, M Kogawa, M Hosokawa… - ISME …, 2022 - academic.oup.com
Single-cell genomics is applied to environmental samples as a method to solve the
problems of current metagenomics. However, in the fluorescence-activated cell sorting …

Epitopes in the capsular polysaccharide and the porin OmpK36 receptors are required for bacteriophage infection of Klebsiella pneumoniae

RA Dunstan, RS Bamert, KS Tan, U Imbulgoda… - Cell Reports, 2023 - cell.com
To kill bacteria, bacteriophages (phages) must first bind to a receptor, triggering the release
of the phage DNA into the bacterial cell. Many bacteria secrete polysaccharides that had …

RaFAH: Host prediction for viruses of Bacteria and Archaea based on protein content

FH Coutinho, A Zaragoza-Solas, M López-Pérez… - Patterns, 2021 - cell.com
Culture-independent approaches have recently shed light on the genomic diversity of
viruses of prokaryotes. One fundamental question when trying to understand their ecological …

Phage therapy: a different approach to fight bacterial infections

Z Hibstu, H Belew, Y Akelew… - Biologics: Targets and …, 2022 - Taylor & Francis
Phage therapy is one of the alternatives to treat infections caused by both antibiotic-sensitive
and antibiotic-resistant bacteria, with no or low toxicity to patients. It was started a century …

Bacteriophages for the targeted control of foodborne pathogens

EW Bumunang, R Zaheer, D Niu, C Narvaez-Bravo… - Foods, 2023 - mdpi.com
Foodborne illness is exacerbated by novel and emerging pathotypes, persistent
contamination, antimicrobial resistance, an ever-changing environment, and the complexity …

Genomic and Biological Profile of a Novel Bacteriophage, Vibrio phage Virtus, Which Improves Survival of Sparus aurata Larvae Challenged with Vibrio harveyi

S Droubogiannis, P Katharios - Pathogens, 2022 - mdpi.com
Due to the emergence of multidrug-resistant bacteria, commonly known as “superbugs”,
phage therapy for the control of bacterial diseases rose in popularity. In this context, the use …

CRISPR-based engineering of phages for in situ bacterial base editing

MA Nethery, C Hidalgo-Cantabrana… - Proceedings of the …, 2022 - National Acad Sciences
Investigation of microbial gene function is essential to the elucidation of ecological roles and
complex genetic interactions that take place in microbial communities. While microbiome …