A plethora of neurological disorders shares a final common deadly pathway known as
excitotoxicity. Among these disorders, ischemic injury is a prominent cause of death and …

Caffeoylquinic acids (CQAs) are a broad class of secondary metabolites that have been
found in edible and medicinal plants from various families. It has been 100 years since the …

Aims Mild traumatic brain injury (mTBI) is an important risk factor for cognitive impairment.
Despite intense efforts to develop efficient treatments, the current therapies are not often …

Epilepsy is a chronic brain disease affecting millions of people worldwide. Anxiety-related
disorders and cognitive deficits are common in patients with epilepsy. Previous studies have …

Alzheimer's disease (AD) is associated with cognitive deficits and behavioral disorders such
as anxiety and depression. Recent clinical and experimental studies have demonstrated that …

Emerging evidence indicates that gut microbiota interacts with immune and nervous systems
in the host and plays a critical role in the pathogenesis of multiple sclerosis (MS) and many …

Alzheimer's disease (AD) is associated with increased depression-related behaviours.
Previous studies have reported a greater risk of AD and depression in women. In recent …

Gestational stress can increase postpartum depression in women. To treat maternal
depression, fluoxetine (FLX) is most commonly prescribed. While FLX may be effective for …

Background: Due to the inflammatory nature of multiple sclerosis (MS), interleukin 6 (IL-6) is
high in blood levels, and it also increases the levels of anxiety related to functional disability …

Stress during pregnancy adversely affects foetal development and leads to later behavioural
outcomes in offspring. Preclinical studies have reported conflicting effects of prenatal stress …