Cortical microcircuits and synaptic transmission in epilepsy

F Doležal - 2024 - dspace.cuni.cz
Epilepsy is a permanent predisposition of the brain to generate epileptic seizures. This
widespread disease significantly impairs patients' life. Since epilepsy is defined only by its …

Transcriptional upregulation as novel gene therapy strategy for neurological disorder

Y Qiu - 2023 - discovery.ucl.ac.uk
Epilepsy remains one of the commonest serious neurological diseases. 30% of people with
epilepsy are refractory to pharmacological treatment, and surgical resection of the focal …

Возможные механизмы влияния супрамамиллярного ядра на функционирование зубчатой извилины и поля СА2 гиппокампа (роль растормаживания)

ИГ Силькис, ВА Маркевич - Нейрохимия, 2020 - elibrary.ru
Проведен анализ возможных механизмов влияния супрамамиллярного ядра
гипоталамуса (СМЯ) на активность гранулярных клеток зубчатой извилины и …

[HTML][HTML] Clinical Neurophysiology of Epileptogenic Networks

N Tsarouchas - Neurophysiology-Networks, Plasticity …, 2022 - intechopen.com
Current theories and models of brain rhythm generation are based on (1) the excitability of
individual neurons and whole networks,(2) the structural and functional connectivity of …

Possible mechanisms of the influence of the supramillary nucleus on the functioning of the dentate gyrus and the CA2 field of the hippocamsus (Role of disinhibition)

IG Silkis, VA Markevich - Neurochemical Journal, 2020 - Springer
We analyzed possible mechanisms of the influence of the supramammillary nucleus of the
hypothalamus (SMN) on the activity of granule cells of the dentate gyrus and pyramidal …

Dorsal and ventral mossy cells differ in their long-range axonal projections throughout the dentate gyrus of the mouse hippocampus

JJ Botterill, KJ Gerencer, KY Vinod… - bioRxiv, 2020 - biorxiv.org
Glutamatergic hilar mossy cells (MCs) have axons that terminate both near and far from their
cell body but stay within the DG, making synapses in the inner molecular layer primarily. The …

Enhancing neuronal inhibition by cell and gene therapy as a novel treatment for Epilepsy

AG Ramos - 2022 - portal.research.lu.se
Epilepsy is a family of heterogeneous and multifactorial neurological disorders, unified by
the occurrence of spontaneous recurrent seizures. Overall, it affects 50 million people …

Temporal lob epi̇lepsi̇si̇ olan bi̇reylerde ve kai̇ni̇k asi̇t i̇le oluşturulan siçan epi̇lepsi̇ modeli̇nde si̇napti̇k vezi̇kül gli̇koprotei̇ni̇ 2 (SV2) …

BA Pazarlar - 2022 - search.proquest.com
Sinaptik vezikül glikoproteini 2A (SV2A), presinaptik vezikülde lokalize olan, levetirasetamı
bağlayan ve muhtemelen hipokampusta inhibitörik nörotransmisyonu düzenleyen bir …

[PDF][PDF] How does the neural circuitry of the hippocampal dentate gyrus shape our memories?

Y Li - research-information.bris.ac.uk
Episodic memory (EM) is the ability to recall a specific episode, such as the temporal
sequence (when), the spatial setting (where) and the people or the objects involved (“what”) …

EI EI Woe: Mossy Cell Regulation of Granule Cell Activity in Temporal Lobe Epilepsy

L Goicouria, J Liu - Epilepsy Currents, 2020 - journals.sagepub.com
An Excitatory and Epileptogenic Effect of Dentate Gyrus Mossy Cells in a Mouse Model of
Epilepsy Botterill JJ, Lu YL, LaFrancois JJ, Bernstein HL, Alcantara-Gonzalez D, Jain S …