Melatonin and its metabolites as chemical agents capable of directly repairing oxidized DNA
A Pérez‐González, R Castañeda‐Arriaga… - Journal of pineal …, 2019 - Wiley Online Library
Oxidative stress mediates chemical damage to DNA yielding a wide variety of products. In
this work, the potential capability of melatonin and several of its metabolites to repair directly …
this work, the potential capability of melatonin and several of its metabolites to repair directly …
Melatonin: A smart molecule in the DNA repair system
SM Mir, A Aliarab, G Goodarzi… - Cell Biochemistry …, 2022 - Wiley Online Library
DNA repair is an important pathway for the protection of DNA molecules from destruction.
DNA damage can be produced by oxidative reactive nitrogen or oxygen species, irritation …
DNA damage can be produced by oxidative reactive nitrogen or oxygen species, irritation …
[HTML][HTML] Melatonin as a harmonizing factor of circadian rhythms, neuronal cell cycle and neurogenesis: additional arguments for its therapeutic use in Alzheimer's …
M Shukla, B Vincent - Current Neuropharmacology, 2023 - ncbi.nlm.nih.gov
The synthesis and release of melatonin in the brain harmonize various physiological
functions. The apparent decline in melatonin levels with advanced aging is an aperture to …
functions. The apparent decline in melatonin levels with advanced aging is an aperture to …
Molecular docking, molecular dynamics, MM/PBSA approaches and bioactivity studies of nepetanudoside B isolated from endemic Nepeta aristata
Nepetanudoside B (NNB) was isolated from aerial parts of endemic Nepeta aristata crude
extract (CH3OH-CHCl3) using silica gel (n-hexane, methanol, ethyl acetate, and …
extract (CH3OH-CHCl3) using silica gel (n-hexane, methanol, ethyl acetate, and …
Precision nutrition to reset virus-induced human metabolic reprogramming and dysregulation (HMRD) in long-COVID
AS Naidu, CK Wang, P Rao, F Mancini… - npj Science of …, 2024 - nature.com
Abstract SARS‐CoV‐2, the etiological agent of COVID-19, is devoid of any metabolic
capacity; therefore, it is critical for the viral pathogen to hijack host cellular metabolic …
capacity; therefore, it is critical for the viral pathogen to hijack host cellular metabolic …
Therapeutic effects of melatonin on endometriosis, targeting molecular pathways: Current knowledge and future perspective
M Sharifi, NR Nikoo, B Badehnoosh… - … -Research and Practice, 2023 - Elsevier
Endometriosis, the very serious disease in women creates a huge financial burden
worldwide, which is comparable to diabetes mellitus. In addition to the typical pelvic pain …
worldwide, which is comparable to diabetes mellitus. In addition to the typical pelvic pain …
Neurotoxicity of bisphenol A and the impact of melatonin administration on oxidative stress, ERK/NF-kB signaling pathway, and behavior in rats
AC Sevastre-Berghian, C Casandra, D Gheban… - Neurotoxicity …, 2022 - Springer
Bisphenol A (BPA) exposure can be associated with neurodevelopmental disorders due to
impairment of cell proliferation and synaptic development. Our study evaluated the effects of …
impairment of cell proliferation and synaptic development. Our study evaluated the effects of …
Mitochondrial melatonin: beneficial effects in protecting against heart failure
Cardiovascular disease is the cause of physical infirmity and thousands of deaths annually.
Typically, during heart failure, cardiomyocyte mitochondria falter in terms of energy …
Typically, during heart failure, cardiomyocyte mitochondria falter in terms of energy …
Potential neuroprotective role of melatonin in sepsis-associated encephalopathy due to its scavenging and anti-oxidative properties
M Sieminski, K Szaruta-Raflesz, J Szypenbejl… - Antioxidants, 2023 - mdpi.com
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host
response to infection. The brain is one of the organs involved in sepsis, and sepsis-induced …
response to infection. The brain is one of the organs involved in sepsis, and sepsis-induced …
Coadministration of melatonin and insulin improves diabetes-induced impairment of rat kidney function
Introduction: The present study was designed to evaluate the therapeutic efficacy of
melatonin and insulin coadministration in diabetes-induced renal injury in rats. Research …
melatonin and insulin coadministration in diabetes-induced renal injury in rats. Research …