Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics

R Tenchov, JM Sasso, X Wang, WS Liaw, CA Chen… - ACS …, 2022 - ACS Publications
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …

Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications

J Mondal, S Pillarisetti, V Junnuthula, M Saha… - Journal of Controlled …, 2023 - Elsevier
Exosomes are endosome-derived nanovesicles involved in cellular communication. They
are natural nanocarriers secreted by various cells, making them suitable candidates for …

Exosomes, a new star for targeted delivery

H Chen, L Wang, X Zeng, H Schwarz… - Frontiers in cell and …, 2021 - frontiersin.org
Exosomes are cell-secreted nanoparticles (generally with a size of 30–150 nm) bearing
numerous biological molecules including nucleic acids, proteins and lipids, which are …

Exosomes: A potential tool for immunotherapy of ovarian cancer

X Gong, H Chi, DF Strohmer, AT Teichmann… - Frontiers in …, 2023 - frontiersin.org
Ovarian cancer is a malignant tumor of the female reproductive system, with a very poor
prognosis and high mortality rates. Chemotherapy and radiotherapy are the most common …

Nanomaterials in anticancer applications and their mechanism of action-A review

CGA Das, VG Kumar, TS Dhas, V Karthick… - … , Biology and Medicine, 2023 - Elsevier
The current challenges in cancer treatment using conventional therapies have made the
emergence of nanotechnology with more advancements. The exponential growth of …

Theranostic signature of tumor-derived exosomes in cancer

S Kumar, R Dhar, LBSS Kumar, GG Shivji, R Jayaraj… - Medical Oncology, 2023 - Springer
Cancer is the most challenging global health crisis. In the recent times, studies on
extracellular vesicles (EVs) are adding a new chapter to cancer research and reports on EVs …

Exosome-based nanomedicine for cancer treatment by targeting inflammatory pathways: current status and future perspectives

MA Ansari, M Thiruvengadam, B Venkidasamy… - Seminars in cancer …, 2022 - Elsevier
Cancer is one of the dreadful diseases worldwide. Surgery, radiation and chemotherapy, are
the three basic standard modes of cancer treatment. However, difficulties in cancer treatment …

Exosomes: promising delivery tools for overcoming blood-brain barrier and glioblastoma therapy

SH Khatami, N Karami, M Taheri-Anganeh… - Molecular …, 2023 - Springer
Gliomas make up virtually 80% of all lethal primary brain tumors and are categorized based
on their cell of origin. Glioblastoma is an astrocytic tumor that has an inferior prognosis …

Translating extracellular vesicle packaging into therapeutic applications

DC Ozkocak, TK Phan, IKH Poon - Frontiers in immunology, 2022 - frontiersin.org
Extracellular vesicles (EVs) are membrane-bound particles released by cells in various
(patho) physiological conditions. EVs can transfer effector molecules and elicit potent …

[HTML][HTML] Glycosylation in extracellular vesicles: Isolation, characterization, composition, analysis and clinical applications

V Vrablova, N Kosutova, A Blsakova, A Bertokova… - Biotechnology …, 2023 - Elsevier
This review provides a comprehensive overview of our understanding of the role that
glycans play in the formation, loading and release of extracellular vesicles (EVs). The …