Cancer is one of the deadliest diseases worldwide. Recent statistics have shown that
metastases and tumor relapse are the leading causes of cancer‐associated deaths. While …

Cancer is the deadliest disease in the world behind heart disease. Sadly, this remains true
even as we suffer the ravages of the Covid-19 pandemic. Whilst current chemo-and …

The great clinical success of cisplatin and its derivatives has convinced people that metal
complexes could play a more significant role in human cancer therapy. However, targeting …

Clinical chemotherapeutic drugs have occasionally been observed to induce antitumor
immune responses beyond the direct cytotoxicity. Such effects are coined as immunogenic …

The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …

Immunogenic cell death (ICD) is a regulated cell death (RCD) pathway. In response to
physical and chemical signals, tumor cells activate specific signaling pathways that stimulate …

Zn1 and Zn2 are Zn-based complexes that activate the immunogenic cell death (ICD) effect
by Ca2+-mediated endoplasmic reticulum stress (ERS) and mitochondrial dysfunction …

The cytolinker and scaffolding protein, plectin, has emerged as a potent driver of malignant
hallmarks in many human cancers due to its involvement in various cellular activities …

Immunogenic cell death (ICD) is a functionally unique form of cell death that promotes a T-
cell-dependent anti-tumor immune response specific to antigens originating from dying …

Undoubtedly, metallomic approaches based on mass spectrometry have evolved into
essential tools supporting the drug development of novel metal-based anticancer drugs …